Sep 1, 1977

Inhibition of neovascularization by an extract derived from vitreous

American Journal of Ophthalmology
I PreisJ Folkman


An extract of the vitreous body, inhibited the growth of new blood vessels induced by tumors in the rabbit cornea. This extract was delivered by an inert, continuously releasing polymer. The average vessel growth rate in the region surrounding the polymer was 32% less in corneas containing the inhibitory substance than in control corneas.

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  • Citations41


Mentioned in this Paper

Blood Vessel
Neoplasm Transplantation
Tissue Extracts
Vitreous Body Structure
Malignant Tumor of Eye
Entire Cornea
Chinchilla Rabbits
Pathologic Neovascularization

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