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Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders

Biochimica Et Biophysica Acta. Molecular Cell Research

Nov 13, 2017

Grzegorz A CzapskiJoanna B Strosznajder

Abstract

Alzheimer's disease (AD) is characterized by the release of amyloid beta peptides (Aβ) in the form of monomers/oligomers which may lead to oxidative stress, mitochondria dysfunction, synaptic loss, neuroinflammation and, in consequence, to overactivation of poly(ADP-ribose) polymerase-1...read more

Mentioned in this Paper

DNM1L gene
GPX1 gene
GPX4 gene
NFE2L1 gene
NFKB1 gene
NRF1 gene
OPA1 gene
SDHA gene
SOD1 gene
TFAM gene
3
18

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Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders

Biochimica Et Biophysica Acta. Molecular Cell Research

Nov 13, 2017

Grzegorz A CzapskiJoanna B Strosznajder

PMID: 29128369

DOI: 10.1016/j.bbamcr.2017.11.003

Abstract

Alzheimer's disease (AD) is characterized by the release of amyloid beta peptides (Aβ) in the form of monomers/oligomers which may lead to oxidative stress, mitochondria dysfunction, synaptic loss, neuroinflammation and, in consequence, to overactivation of poly(ADP-ribose) polymerase-1...read more

Mentioned in this Paper

DNM1L gene
GPX1 gene
GPX4 gene
NFE2L1 gene
NFKB1 gene
NRF1 gene
OPA1 gene
SDHA gene
SOD1 gene
TFAM gene
3
18

Similar Papers Found In These Feeds

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