PMID: 591113Jan 1, 1977

Inhibition of specific immune responses by feeding protein antigens

International Archives of Allergy and Applied Immunology
D G HansonC A Roy

Abstract

A profound and long-lasting state of specific immune unresponsiveness may be induced in adult inbred mice given a single dose of protein immunogens--such as ovalbumin or hemocyanin--by the digestive route. The degree of unresponsiveness induced by intragastric exposure to ovalbumin could not be achieved by intravenous injection of deaggregated ovalbumin solutions across a wide range of doses. Unresponsiveness induced by intragastric exposure to hapten-protein conjugates is specific to the carrier protein.

Citations

Aug 1, 1995·International Journal for Parasitology·A CuisonY Nakajima
Nov 1, 1979·Veterinary Immunology and Immunopathology·T J NewbyF J Bourne
Jun 8, 2002·Toxicology Letters·R PietersS Nierkens
Sep 1, 1980·The Journal of Experimental Medicine·J A MattinglyC A Janeway
Jun 28, 2012·Clinical & Developmental Immunology·Bo JinAnthony E T Yeo
Sep 29, 2011·Clinical & Developmental Immunology·Bernardo Sgarbi Reis, Daniel Mucida
Jan 10, 2012·Annual Review of Immunology·Angelina M Bilate, Juan J Lafaille
Jul 1, 2014·Human Immunology·Adam S A Gracon, David S Wilkes
May 1, 1996·Journal of Neuroimmunology·K A Kelly, C C Whitacre
Dec 15, 2015·Immunobiology·Raquel Alves CostaCláudia Rocha Carvalho
Oct 22, 2008·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Henry Yim Wu
Apr 1, 1997·Medical Hypotheses·J Eldor
Aug 1, 1984·The Journal of Surgical Research·W E KoisD C Dafoe
Feb 13, 2013·Cellular Immunology·Archimedes Barbosa Castro-JuniorN M Vaz
Feb 15, 2001·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·B A VerdolinC R Carvalho
Mar 16, 2017·Immunology·Thiago Anselmo CantarutiCláudia Rocha Carvalho
May 1, 1978·Medical Hypotheses·N M Vaz, F J Varela
Feb 1, 1996·Baillière's Clinical Rheumatology·M F Kagnoff
Jun 29, 2006·Journal of Nutritional Science and Vitaminology·Alizadeh MohammadTohru Sakai
Jan 1, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Chantal KuhnHoward L Weiner
Jun 1, 1994·Scandinavian Journal of Immunology·C R CarvalhoN M Vaz
Jan 1, 1993·European Journal of Immunology·J D PetersonS D Miller
Jan 1, 1985·Scandinavian Journal of Gastroenterology. Supplement·C O Elson
Jan 1, 1990·Clinical and Experimental Immunology·R B JohnsonJ H Skerritt
Jan 1, 1982·Annals of the New York Academy of Sciences·M F Kagnoff
Apr 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Karen M SmithPaul Garside
Oct 25, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·C A BlackR P Edwards
Jan 1, 1993·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·L A HansonU Dahlgren
Mar 1, 1996·Clinical and Experimental Immunology·D C Wraith
Aug 1, 1986·The American Journal of Physiology·P R HarmatzW A Walker

Related Concepts

Antibody Formation
Antigens
Dinitrobenzenes
Hemocyanin
Natural Immunosuppression
Injections, Intraperitoneal
Intravenous Injections
Intubation, Nasogastric
Mice, Inbred C57BL
Mice, Inbred DBA

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