Inhibition of sperm migration through cervical mucus in vitro

Fertility and Sterility
S P Lorton, N L First


The effectiveness of inhibiting bovine sperm migration through cervical mucus in vitro by prior treatment of semen with 45 to 150 micrograms of soybean trypsin inhibitor, univalent (papain-digested, nonagglutinating) and bivalent (undigested) rabbit anti-bovine sperm immunoglobulin, and heat-treated heifer serum was studied. Sperm head-to-head agglutination resulted from treatment of semen with bivalent immune antibody and heat-treated heifer serum. Migration through cervical mucus was inhibited only by treatment resulting in spermagglutination. It is postulated that in vivo inhibition of sperm migration may be influenced by secretory immunoglobulins from the cervix.


Jun 1, 1980·International Journal of Andrology·W W Tso, W M Lee

Related Concepts

Bos indicus
Palm-Leaf Reaction
Hot Temperature
Sperm Transport
Y-Chromosome-Bearing Sperm
Trypsin Inhibitors
In Vitro [Publication Type]

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.