PMID: 14228140Oct 1, 1964Paper

INHIBITION OF SYMPATHOMIMETIC EFFECTS ON THE HEART

British Journal of Pharmacology and Chemotherapy
B G BENFEY, D R VARMA

Abstract

The adrenaline beta-receptor blocking drug, pronethalol, and the sympathomimetic amines, (-)-ephedrine, (-)-amphetamine, dexamphetamine, (-)-Psi-ephedrine and tyramine, inhibited the sympathomimetic effects of butyrylcholine and tyramine on the guinea-pig isolated atrium. Being reversible and noncompetitive, this antagonism was unspecific and not due to blockade of adrenaline receptors, although pronethalol inhibited the effect of noradrenaline competitively.

References

Mar 1, 1959·British Journal of Pharmacology and Chemotherapy·O ARUNLAKSHANA, H O SCHILD
Oct 1, 1961·British Journal of Pharmacology and Chemotherapy·B G BENFEY, K GREEFF
Jul 1, 1963·The Journal of Physiology·C B FERRY
Dec 1, 1963·British Journal of Pharmacology and Chemotherapy·A SEKIYA, E M VAUGHANWILLIAMS
Jun 15, 1944·The Journal of Physiology·E Bülbring
Mar 1, 1962·The Journal of Physiology·L Szekeres, E M Williams

Citations

Aug 1, 1967·Comparative Biochemistry and Physiology·F MichalR H Thorp
Jan 1, 1966·British Journal of Pharmacology and Chemotherapy·B G BENFEY, D R Varma
Dec 1, 1966·British Journal of Pharmacology and Chemotherapy·I BrickI C Roddie
Mar 1, 1968·British Journal of Pharmacology and Chemotherapy·K Shimamoto, N Toda
Jun 1, 1975·British Journal of Pharmacology·I M James, L Macdonell
Apr 1, 1967·Acta Physiologica Scandinavica·L Hirvonen, T O Paavilainen
Nov 27, 2007·European Journal of Pharmacology·Rapheeporn KhwanchueaChaweewan Jansakul

Related Concepts

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.