PMID: 2429647Jan 1, 1986Paper

Inhibitors of coagulation-fibrinolysis system and platelet function in patients with vertigo

Auris, Nasus, Larynx
Y NodaT Kosugi

Abstract

Eight parameters of blood coagulation and fibrinolysis, i.e., the levels of fibrinogen, plasminogen, fibrinogen and/or fibrin-degradation products (FDP), alpha 2-macroglobulin, alpha 1-antitrypsin, CI-inactivator, antiplasmin activity and antithrombin activity, were measured in patients with vertigo. Furthermore, the ADP- and collagen-induced platelet aggregations were determined. The results were compared with those for healthy adults. The antiplasmin activity was significantly reduced (p is less than 0.001), the antithrombin activity was significantly reduced (p is less than 0.001) and the platelet aggregation significantly increased (p is less than 0.001), but the levels of fibrinogen, plasminogen, FDP, alpha 2-macroglobulin, alpha 1-antitrypsin and CI-inactivator were not significantly altered. The importance of the coagulation-fibrinolysis system and platelet function in patients with vertigo is discussed.

References

Sep 1, 1977·Scandinavian Journal of Clinical and Laboratory Investigation·A C Teger-NilssonE Gyzander
Apr 1, 1977·Thrombosis Research·P J GaffneyT B Kirkwood
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Aug 1, 1963·The Journal of Physiology·G V BORN, M J CROSS

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