Inhibitory control of reaching movements in humans.

Experimental Brain Research
Giovanni MirabellaStefano Ferraina

Abstract

Behavioral flexibility provides a very large repertoire of actions and strategies, however, it carries a cost: a potential interference between different options. The voluntary control of behavior starts exactly with the ability of deciding between alternatives. Certainly inhibition plays a key role in this process. Here we examined the inhibitory control of reaching arm movements with the countermanding paradigm. Right-handed human subjects were asked to perform speeded reaching movements toward a visual target appearing either on the same or opposite side of the reaching arm (no-stop trials), but to withhold the commanded movement whenever an infrequent stop signal was presented (stop trials). As the delay between go and stop signals increased, subjects increasingly failed to inhibit the movement. From this inhibitory function and the reaction times of movements in no-stop trials, we estimated the otherwise unobservable duration of the stopping process, the stop signal reaction time (SSRT). We found that the SSRT for reaching movements was, on average, 206 ms and that it varied with the reaching arm and the target position even though the stop signal was a central stimulus. In fact, subjects were always faster to withhold rea...Continue Reading

Associated Clinical Trials

Sep 11, 2018·Giovanni Mirabella

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Citations

Sep 28, 2007·Experimental Brain Research·Stéphanie Rossit, Monika Harvey
Sep 18, 2008·Experimental Brain Research·Giovanni MirabellaStefano Ferraina
Jul 1, 2009·Experimental Brain Research·Welber MarinovicJames R Tresilian
Apr 21, 2009·Cognitive Neuropsychology·Giovanni MirabellaStefano Ferraina
Nov 27, 2009·Journal of Neurophysiology·Veit StuphornJeffrey D Schall
Jul 5, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Maurizio MattiaStefano Ferraina
Jan 31, 2014·Experimental Brain Research·Paolo Federico, Giovanni Mirabella
Apr 13, 2011·Research in Developmental Disabilities·Emiliano BrunamontiStefano Ferraina
Sep 30, 2008·Neuroscience and Biobehavioral Reviews·Frederick Verbruggen, Gordon D Logan
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Jun 5, 2015·Frontiers in Behavioral Neuroscience·Valentina MioneStefano Ferraina
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