Inhibitory control test for the diagnosis of minimal hepatic encephalopathy

Gastroenterology
Jasmohan S BajajKia Saeian

Abstract

Minimal hepatic encephalopathy (MHE) is difficult to diagnose. The Inhibitory Control Test (ICT) measures response inhibition and has diagnosed MHE with 90% sensitivity and specificity in a selected population; high lure and low target rates indicated poor ICT performance. We studied the reliability and validity of ICT for MHE diagnosis. ICT was compared with a psychometric battery (standard psychometric tests [SPT]) for MHE diagnosis and overt hepatic encephalopathy (OHE) prediction. ICT was administered twice for test-retest reliability, before/after transvenous intrahepatic portosystemic shunting (TIPS), and before/after yogurt treatment. The time taken by 2 medical assistants (MA) to administer ICT was recorded and compared with that of a psychologist for cost analysis. One hundred thirty-six cirrhotic patients and 116 age/education-matched controls were studied. ICT (>5 lures) had 88% sensitivity for MHE diagnosis with 0.902 area under the curve for receiver operating characteristic. MHE-positive patients had significantly higher ICT lures (11 vs 4, respectively, P = .0001) and lower targets (92% vs 97%, respectively, P = .0001) compared with MHE-negative patients. The test/retest reliability for ICT lures (n = 50, r = 0.9...Continue Reading

Citations

Apr 11, 2009·Gut·A MencinR F Schwabe
Jul 24, 2012·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jasmohan S BajajPatrick M Gillevet
Sep 24, 2011·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jasmohan S BajajPatrick M Gillevet
Jun 13, 2012·World Journal of Gastroenterology : WJG·Takumi KawaguchiMichio Sata
Dec 15, 2012·World Journal of Gastroenterology : WJG·Matteo GarcovichAntonio Gasbarrini
Jan 16, 2013·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Praveen SharmaAshish Kumar
May 18, 2011·World Journal of Gastrointestinal Pharmacology and Therapeutics·Oliviero RiggioChiara Pasquale
Mar 7, 2014·The American Journal of Gastroenterology·Erica V TartaglioneGeorge N Ioannou
Sep 9, 2011·Digestive Diseases and Sciences·Jasmohan S BajajJames B Wade
May 27, 2011·Scandinavian Journal of Gastroenterology·Søren Schou OlesenAsbjørn Mohr Drewes
Jun 26, 2009·Expert Opinion on Emerging Drugs·Oliviero Riggio, Lorenzo Ridola
Dec 31, 2014·International Journal of Hepatology·Saurav DasJayanthi Venkataraman
Dec 14, 2016·The American Journal of Gastroenterology·Jasmohan S BajajJames B Wade
Sep 2, 2016·Therapeutic Advances in Gastroenterology·Nasser MousaWaleed Eldars
Apr 7, 2017·Clinical and Translational Gastroenterology·Jasmohan S Bajaj
Mar 9, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Francesca CampagnaPiero Amodio
Sep 30, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Richard M Dubinsky, Anthony C Stein
Dec 21, 2013·Current Gastroenterology Reports·Eiman Nabi, Jasmohan S Bajaj
Dec 28, 2016·Journal of Clinical Gastroenterology·Jawaid Shaw, Jasmohan S Bajaj
May 24, 2017·Gastroenterology Report·Peter Ferenci
Jun 29, 2010·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Rajagopal ChadalavadaKevin Mullen
Jul 27, 2017·The Cochrane Database of Systematic Reviews·Ee Teng GohLise Lotte Gluud
Mar 14, 2018·The American Journal of Gastroenterology·Elliot B TapperAnna S-F Lok
Apr 7, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Piero Amodio
May 9, 2015·World Journal of Hepatology·Antonio SolinasAngelo Deplano
Oct 28, 2010·The American Journal of Gastroenterology·Eva RománGermán Soriano
Aug 13, 2010·Nature Reviews. Gastroenterology & Hepatology·Ravi Prakash, Kevin D Mullen
Mar 12, 2009·The American Journal of Gastroenterology·Jasmohan S BajajKia Saeian
May 16, 2018·The Cochrane Database of Systematic Reviews·Ee Teng GohMarsha Y Morgan
Feb 8, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jasmohan S BajajJames B Wade
Jun 8, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Jasmohan S BajajJames B Wade
Nov 2, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Elliot B TapperGrace L Su
Nov 15, 2018·Journal of Translational Internal Medicine·Herbert Djiambou-Nganjeu
May 11, 2011·The American Journal of Gastroenterology·Jasmohan S BajajArun J Sanyal
Nov 2, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Elliot B TapperAnna S Lok
Dec 17, 2009·Alimentary Pharmacology & Therapeutics·J S Bajaj
Mar 10, 2010·Metabolic Brain Disease·Jasmohan S Bajaj
Jun 17, 2009·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Radha K Dhiman, Yogesh K Chawla
Dec 19, 2008·Expert Review of Gastroenterology & Hepatology·Jasmohan S Bajaj
Jul 3, 2010·Journal of Gastroenterology and Hepatology·Radha K DhimanUNKNOWN Indian National Association for Study of the Liver
Jun 10, 2010·Expert Review of Gastroenterology & Hepatology·Mark J W McPhailSimon D Taylor-Robinson
Oct 7, 2010·Current Gastroenterology Reports·Jennifer Y Montgomery, Jasmohan S Bajaj
Jun 18, 2019·The Cochrane Database of Systematic Reviews·Harry D ZachariasMarsha Y Morgan

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