Sep 1, 1982

Inhibitory effect of fibronectin on the fibrin formation

Thrombosis Research
J Niewiarowska, C S Cierniewski

Abstract

125I-fibronectin is incorporated into fibrin when blood plasma is clotted with thrombin. This process is dependent upon fibronectin concentration, temperature, and the presence of calcium ions. Fibronectin appears to be a very strong inhibitor of fibrin formation and influences both the thrombin clotting time and fibrin quality.

  • References15
  • Citations10
  • References15
  • Citations10

Mentioned in this Paper

Fibrin Measurement
Thrombin Time Assay
Depression, Chemical
Calcium
Hormone Receptors, Cell Surface
F2 gene
Thrombin
Calcium ion
Receptors, Fibronectin
Plasma

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.