PMID: 799314Dec 1, 1976Paper

Inhibitory effect of midbrain raphe stimulation on the maintenance of an active avoidance reflex

Pharmacology, Biochemistry, and Behavior
G L Kovács, G Telegdy


Performance of an active avoidance (bench-jumping) reflex has been studied in rats during stimulation of the midbrain raphe nuclei. Raphe stimulation (10 cps, 0.2 msec, 2.5-5.0 V) inhibited the performance of the reflex. A serotonin receptor blocker (methysergide, 2.0 mg/kg IP) increased the reflex performance in non-stimulated animals and prevented the action of raphe stimulation. The data indicate that the cerebral serotoninergic system might have an inhibitory control over the performance of conditioned avoidance reflex.


Apr 30, 1976·Brain Research·E T PierceJ A Hobson
Apr 21, 1967·Science·G K AghajanianM H Sheard
Jan 1, 1969·Annual Review of Psychology·R W Doty

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Aug 1, 1980·Physiology & Behavior·W KostowskiA Płaźnik
Jan 1, 1988·Physiology & Behavior·S SakhiE Tobach

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