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Inhibitory effects of antihistamines and antiserotonins on the bone marrow reactions produced by Escherichia coli endotoxin in mice

The Journal of Infectious Diseases

Dec 1, 1975

M Hirata

PMID: 442

Abstract

The bone marrow reactions (that is, decrease of nucleated cell counts and increase of red blood cell counts) of mouse bone were observed 1 hr after injection of endotoxin and peaked after 18 hr. These reactions were significantly inhibited when diphenhydramine, promethazine (antihistami...read more

Mentioned in this Paper

Histamine
Ceplene
Injection Procedure
Administration Procedure
Laboratory mice
Skeletal Bone
Antihistamines, Classical
Antihistamines
Promethazine
Rumergan
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Inhibitory effects of antihistamines and antiserotonins on the bone marrow reactions produced by Escherichia coli endotoxin in mice

The Journal of Infectious Diseases

Dec 1, 1975

M Hirata

PMID: 442

DOI:

Abstract

The bone marrow reactions (that is, decrease of nucleated cell counts and increase of red blood cell counts) of mouse bone were observed 1 hr after injection of endotoxin and peaked after 18 hr. These reactions were significantly inhibited when diphenhydramine, promethazine (antihistami...read more

Mentioned in this Paper

Histamine
Ceplene
Injection Procedure
Administration Procedure
Laboratory mice
Skeletal Bone
Antihistamines, Classical
Antihistamines
Promethazine
Rumergan

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Paper Details
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