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Inhibitory effects of antihistamines and antiserotonins on the bone marrow reactions produced by Escherichia coli endotoxin in mice

The Journal of Infectious Diseases

Dec 1, 1975

M T A Hirata

PMID: 442

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Abstract

The bone marrow reactions (that is, decrease of nucleated cell counts and increase of red blood cell counts) of mouse bone were observed 1 hr after injection of endotoxin and peaked after 18 hr. These reactions were significantly inhibited when diphenhydramine, promethazine (antihistami...read more

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Skeletal Bone
Viternum
Diphenhydramine
Serotonin Antagonists
Luminal
Endotoxins
Metazoa
Ceplene
Chlorpromazine
Bone Marrow Diseases
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  • Inhibitory effects of antihistamines and antiserotonins on the bone marrow reactions produced by Escherichia coli endotoxin in mice

    The Journal of Infectious Diseases

    Dec 1, 1975

    M T A Hirata

    PMID: 442

    DOI:

    Abstract

    The bone marrow reactions (that is, decrease of nucleated cell counts and increase of red blood cell counts) of mouse bone were observed 1 hr after injection of endotoxin and peaked after 18 hr. These reactions were significantly inhibited when diphenhydramine, promethazine (antihistami...read more

    Mentioned in this Paper

    Skeletal Bone
    Viternum
    Diphenhydramine
    Serotonin Antagonists
    Luminal

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