Inhibitory interactions among olfactory glomeruli do not necessarily reflect spatial proximity.

Journal of Neurophysiology
Carolina E ReisenmanJ G Hildebrand

Abstract

Inhibitory interactions shape the activity of output neurons in primary olfactory centers and promote contrast enhancement of odor representations. Patterns of interglomerular connectivity, however, are largely unknown. To test whether the proximity of glomeruli to one another is correlated with interglomerular inhibitory interactions, we used intracellular recording and staining methods to record the responses of projection (output) neurons (PNs) associated with glomeruli of known olfactory tuning in the primary olfactory center of the moth Manduca sexta. We focused on Toroid I, a glomerulus in the male-specific macroglomerular complex (MGC) specialized to one of the two key components of the conspecific females' sex pheromone, and the adjacent, sexually isomorphic glomerulus 35, which is highly sensitive to Z-3-hexenyl acetate (Z3-6:OAc). We used the two odorants to activate these reference glomeruli and tested the effects of olfactory activation in other glomeruli. We found that Toroid-I PNs were not inhibited by input to G35, whereas G35 PNs were inhibited by input to Toroid-I PNs. We also recorded the responses of PNs arborizing in other sexually isomorphic glomeruli to stimulation with the sex pheromone and Z3-6:OAc. We f...Continue Reading

References

Jan 1, 1986·Cell and Tissue Research·S G HoskinsJ G Hildebrand
May 1, 1987·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·T A Christensen, J G Hildebrand
Oct 1, 1972·Physiological Reviews·G M Shepherd
Apr 11, 1995·Proceedings of the National Academy of Sciences of the United States of America·M YokoiS Nakanishi
Jun 1, 1994·Journal of Neurophysiology·D A BerkowiczG M Shepherd
Oct 1, 1993·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·T A ChristensenJ G Hildebrand
Feb 15, 1993·Microscopy Research and Technique·J Boeckh, L P Tolbert
Jan 1, 1996·Brain Research Bulletin·W T NickellM M Behbehani
Nov 15, 1996·Cell·P MombaertsR Axel
Apr 29, 1998·The Journal of Comparative Neurology·B A JohnsonM Leon
Mar 25, 1999·Cell·B MalnicL B Buck
Jun 22, 2000·The Journal of Comparative Neurology·F XuG M Shepherd
Aug 16, 2000·Cell·L B VosshallR Axel
Apr 6, 2001·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·V D Shields, J G Hildebrand
Aug 9, 2001·The Journal of Comparative Neurology·R AbelR Menzel
Nov 14, 2001·Chemical Senses·B KalinováB S Hansson
Feb 28, 2002·Current Opinion in Neurobiology·Gregory S X E JefferisLiqun Luo
Apr 25, 2003·Journal of Neurophysiology·Brian Halabisky, Ben W Strowbridge
May 10, 2003·Phytochemistry·Robert A RagusoLucinda A McDade
Sep 2, 2003·Trends in Neurosciences·Nathan E Schoppa, Nathan N Urban
Dec 12, 2003·Nature·J L AungstM T Shipley
Dec 20, 2003·Science·Rachel I WilsonGilles Laurent
Feb 13, 2004·Journal of Neurophysiology·Rainer W Friedrich, Gilles Laurent
Feb 13, 2004·Journal of Neurophysiology·Shin NagayamaKensaku Mori
Mar 19, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carolina E ReisenmanJohn G Hildebrand
Mar 23, 2004·Nature Reviews. Neuroscience·Peter Mombaerts
Jun 24, 2004·Cell·Elissa A HallemJohn R Carlson
Sep 21, 2004·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·T HeinbockelJ G Hildebrand
Sep 2, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carolina E ReisenmanJohn G Hildebrand
Oct 7, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rachel I Wilson, Gilles Laurent
Dec 2, 2005·Journal of Neurophysiology·Dejan VucinićEfstratios K Kosmidis
Apr 18, 2006·Cell·Elissa A Hallem, John R Carlson
Jun 29, 2007·Proceedings of the National Academy of Sciences of the United States of America·Cory M RootJing W Wang
Nov 6, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ana F Silbering, C Giovanni Galizia

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Citations

Feb 3, 2011·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Carolina E ReisenmanJohn G Hildebrand
Jul 31, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Thomas HeinbockelCarolina E Reisenman
Nov 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey A RiffellJohn G Hildebrand
Aug 2, 2011·Integrative and Comparative Biology·Jeffrey A Riffell
May 7, 2014·Chemical Senses·Antoine ChaffiolSylvia Anton
Jun 26, 2014·Biological cybernetics·Marie LevakovaPetr Lansky
Oct 30, 2009·Journal of Neurogenetics·Andrew M DacksJing W Wang
Oct 4, 2011·Progress in Neurobiology·Joshua P MartinJohn G Hildebrand
Jun 10, 2010·The Journal of Comparative Neurology·Andrew M DacksAlan J Nighorn
Apr 5, 2014·The European Journal of Neuroscience·C Giovanni Galizia
Sep 1, 2015·Frontiers in Physiology·Carolina E Reisenman, Jeffrey A Riffell
Mar 20, 2012·Current Opinion in Neurobiology·Jeffrey A Riffell
Jun 2, 2015·Frontiers in Physiology·Angéla RouyarSylvia Anton
Oct 27, 2012·Journal of Neurophysiology·Cyrille C GirardinC Giovanni Galizia
Jul 23, 2016·Frontiers in Physiology·Carolina E ReisenmanPablo G Guerenstein

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