PMID: 9556769Apr 29, 1998Paper

Inhibitory processes in covert orienting in patients with Alzheimer's disease

Neuropsychology
J DanckertJ Currie

Abstract

Previous studies of covert orienting in Alzheimer's disease (AD) have investigated exogenous and endogenous processes separately. We aimed to investigate how the 2 modes of orienting interact to control attention in healthy older participants and patients with AD. The covert orienting of visual attention task (COVAT) with abrupt onset cues was used in all experiments. In Experiments 1 and 2, predictive information was added to cues to initiate an endogenous orienting response. Results showed that healthy older participants were able to use endogenous processes to inhibit exogenous orienting. In contrast, patients with AD were unable to inhibit exogenous orienting to cues even when targets rarely appeared there. Experiment 3 investigated inhibition of return (IOR) in patients with AD. Both healthy older controls and patients with AD showed a normal IOR, suggesting that exogenous orienting processes are relatively unaffected by the normal aging process or in patients with AD. A model of covert orienting in which exogenous and endogenous orienting processes interact to control attentional behaviors is discussed.

Citations

Sep 5, 2002·Neuropsychologia·Andrea TalesRobert J Snowden
Apr 13, 2002·Neuropsychology·Raja ParasuramanTrey Sunderland
Dec 19, 2007·Journal of Experimental Psychology. Human Perception and Performance·Alexandra List, Lynn C Robertson
Oct 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Laura BusseStefan Treue
Jul 29, 2010·Journal of the International Neuropsychological Society : JINS·Jeannette R MahoneyRoee Holtzer
Apr 20, 2019·Developmental Neuropsychology·Alma GuilbertChristine Moroni

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