Inhospital Mortality in Patients with Type 2 Diabetes Mellitus: A Prospective Cohort Study in Lima, Peru

Journal of Diabetes Research
Henry ZeladaHelard Manrique

Abstract

Objective. To estimate cause of death and to identify factors associated with risk of inhospital mortality among patients with T2D. Methods. Prospective cohort study performed in a referral public hospital in Lima, Peru. The outcome was time until event, elapsed from hospital admission to discharge or death, and the exposure was the cause of hospital admission. Cox regression was used to evaluate associations of interest reporting Hazard Ratios (HR) and 95% confidence intervals. Results. 499 patients were enrolled. Main causes of death were exacerbation of chronic renal failure (38.1%), respiratory infections (35.7%), and stroke (16.7%). During hospital stay, 42 (8.4%) patients died. In multivariable models, respiratory infections (HR = 6.55, p < 0.001), stroke (HR = 7.05, p = 0.003), and acute renal failure (HR = 16.9, p = 0.001) increased the risk of death. In addition, having 2+ (HR = 7.75, p < 0.001) and 3+ (HR = 21.1, p < 0.001) conditions increased the risk of dying. Conclusion. Respiratory infections, stroke, and acute renal disease increased the risk of inhospital mortality among hospitalized patients with T2D. Infections are not the only cause of inhospital mortality. Certain causes of hospitalization require standardi...Continue Reading

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Citations

Oct 7, 2016·Diabetes Technology & Therapeutics·Christopher G ParkinRolf Hinzmann
Sep 17, 2018·Journal of Diabetes Investigation·Lik-Hui LauElif I Ekinci
Jun 10, 2020·Endocrinología, Diabetes Y Nutrición·María Paula RussoDiego H Giunta
May 24, 2021·Revue D'épidémiologie Et De Santé Publique·A Gómez-GómezD E Noyola
Jul 17, 2021·Endocrinología, Diabetes Y Nutrición·María Paula RussoDiego H Giunta

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