PMID: 2463552Nov 1, 1988Paper

Initial clinical experience with a minute ventilation sensing rate modulated pacemaker: improvements in exercise capacity and symptomatology

Pacing and Clinical Electrophysiology : PACE
C P LauA J Camm

Abstract

A minute ventilation sensing rate modulated pacemaker was implanted in nine patients with bradycardia. Minute ventilation is sensed in this pacemaker by means of a standard bipolar pacing electrode. Compared with exercise in the constant rate ventricular pacing (VVI) mode at 1 month after pacemaker implantation, rate responsive pacing resulted in an improvement of exercise capacity of 33 +/- 5% (from 437 +/- 42 s in the VVI mode to 593 +/- 57 s in the rate modulated mode, P less than 0.01, Bruce protocol). This improvement was maintained in the seven patients in whom an exercise test was repeated at 3 months after implantation. The pacing rate was significantly correlated with oxygen consumption (r = 0.84 +/- 0.04) and measured minute ventilation (r = 0.76 +/- 0.06). Symptomatology in these patients was assessed by means of self-assessment questionnaires in a double blind, randomized cross-over study in which the pacemaker was alternatively programmed into the VVI and rate modulated modes. Significant improvements in "shortness of breath" and "energy during daily activities" were documented during rate modulated pacing and "palpitations" and "chest pain" were not worsened. Most patients preferred the rate modulated mode during ...Continue Reading

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Citations

Mar 12, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Frieder Braunschweig
Jul 1, 1993·The American Journal of Cardiology·Y SeinoH Hayakawa
Mar 1, 1990·Current Problems in Cardiology·S Furman, J Gross
Apr 1, 1989·The American Journal of Cardiology·C P LauA J Camm
Mar 10, 2000·Cardiology Clinics·S K Leung, C P Lau
Apr 15, 1992·The American Journal of Cardiology·M BorganelliJ J Langberg
Mar 1, 1995·Pacing and Clinical Electrophysiology : PACE·I OvsyshcherC Bondy
Feb 1, 1990·Pacing and Clinical Electrophysiology : PACE·C P LauW H Leung
Dec 19, 1998·Journal of Cardiopulmonary Rehabilitation·C T SharpR G Haennel
Oct 1, 1990·Circulation·S Furman
Oct 1, 1990·Pacing and Clinical Electrophysiology : PACE·C P LauW H Leung
Aug 1, 1992·Pacing and Clinical Electrophysiology : PACE·C P Lau
Apr 1, 1993·Pacing and Clinical Electrophysiology : PACE·M R PitneyM J Davis
Dec 11, 1990·Pacing and Clinical Electrophysiology : PACE·S M YabekB McWilliams
Aug 30, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michael GliksonUNKNOWN ESC Scientific Document Group
Aug 30, 2021·European Heart Journal·Michael GliksonUNKNOWN ESC Scientific Document Group

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