PMID: 46334Jan 4, 1975

Initial effect of injury on ketone bodies and other blood metabolites

R SmithK G Alberti


The arterial and venous concentrations of ketone bodies and other metabolites were measured in twelve adults, from 2 to 24 hours after injury. Two groups could be distinguished, with or without hyperketonaemia (defined as more than 0.2 mmol per litre) in the 2-hour blood-sample. In the hyperdetonaemic group the concentrations of alanine, pyruvate, and lactate and the urinary nitrogen excretion were lower throughout the first 24 hours than in the non-hyperdetonaemic group. These preliminary results indicate that hyperketonaemia after trauma is associated with decreased protein breakdown.


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Related Concepts

Collection of Blood Specimen for Laboratory Procedure
Pyruvate Measurement
Ketone Bodies Measurement, Quantitative
Lactic Acid Measurement
Temporal Region Trauma
Body Excretions

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