Initial experience of EUS-guided radiofrequency ablation of unresectable pancreatic cancer

Gastrointestinal Endoscopy
Tae Jun SongMyung-Hwan Kim

Abstract

Radiofrequency ablation (RFA) has been used as a valuable treatment modality for various unresectable malignancies. EUS-guided radiofrequency ablation (EUS-RFA) of the porcine pancreas was reported to be feasible and safe in our previous study, suggesting that EUS-RFA may be applicable as an adjunct and effective alternative treatment method for unresectable pancreatic cancer. This study aimed to assess the technical feasibility and safety of EUS-RFA for unresectable pancreatic cancer. An 18-gauge endoscopic RFA electrode and a radiofrequency generator were used for the procedure. The length of the exposed tip of the RFA electrode was 10 mm. After insertion of the RFA electrode into the mass, the radiofrequency generator was activated to deliver 20 to 50 W ablation power for 10 seconds. Depending on tumor size, the procedure was repeated to sufficiently cover the tumor. EUS-RFA was performed successfully in all 6 patients (median age 62 years, range 43-73 years). Pancreatic cancer was located in the head (n = 4) or body (n = 2) of the pancreas. The median diameter of masses was 3.8 cm (range 3cm-9cm). Four patients had stage 3 disease, and 2 patients had stage 4 disease. After the procedure, 2 patients experienced mild abdomina...Continue Reading

References

Sep 13, 2006·Journal of Surgical Oncology·Yulian WuHaichao Yan
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·P HadjicostasP Symeonides
Jan 14, 2010·The British Journal of Surgery·R GirelliC Bassi
Jan 14, 2012·Clinical & Developmental Immunology·Sebastian P HaenCécile Gouttefangeas
May 29, 2012·Gastrointestinal Endoscopy Clinics of North America·Won Jae Yoon, William R Brugge
Jun 1, 2012·The British Journal of Surgery·M CantoreC Bassi
Oct 11, 2012·Gastroenterology Research and Practice·Monica GaidhaneMichel Kahaleh
Oct 20, 2012·Gastrointestinal Endoscopy·Hong Jun KimMyung-Hwan Kim
Apr 18, 2013·Journal of Hepato-biliary-pancreatic Sciences·Isabella FrigerioClaudio Bassi

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Citations

Mar 17, 2016·Gastroenterology Research and Practice·Salvatore PaiellaClaudio Bassi
Aug 2, 2016·Canadian Journal of Gastroenterology & Hepatology·Kinesh ChangelaVinaya Gaduputi
Feb 9, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Sundeep Lakhtakia, Dong-Wan Seo
Feb 6, 2017·Digestive Diseases and Sciences·Tarun Rustagi, Ankit Chhoda
Jul 12, 2017·Pancreas·Adrianne TsenLaura Rosenkranz
Mar 27, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Jun-Ho ChoiSung Koo Lee
Nov 16, 2018·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Paola SaccomandiGiuseppe Quero
Jan 23, 2019·Clinical Endoscopy·Zaheer Nabi, D Nageshwar Reddy
Aug 9, 2017·World Journal of Gastroenterology : WJG·Satyarth Chaudhary, Si-Yu Sun
Jul 25, 2019·Clinical Endoscopy·Yousuke NakaiKazuhiko Koike
Mar 7, 2017·Journal of Clinical Gastroenterology·Tarun RustagiMichael J Levy
Jun 3, 2020·Journal of Clinical Gastroenterology·Giuseppe VanellaPaolo G Arcidiacono
Oct 13, 2016·World Journal of Gastroenterology : WJG·María-Victoria Alvarez-Sánchez, Bertrand Napoléon
Jul 28, 2016·Current Opinion in Gastroenterology·Alexander M SarkisianReem Z Sharaiha
Apr 17, 2020·Endoscopic Ultrasound·Sabrina Gloria Giulia TestoniPaolo Giorgio Arcidiacono
Apr 11, 2017·Clinical Endoscopy·Jimin Han, Kenneth J Chang
Jan 31, 2017·Journal of Digestive Diseases·Woo Hyun Paik, Dong Wan Seo
Dec 14, 2016·Asian Pacific Journal of Tropical Medicine·Tejas Kirtane, Manoop S Bhutani
Jan 25, 2018·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Sang Hyub Lee
Oct 6, 2020·Endoscopy International Open·Amaninder DhaliwalDouglas G Adler
May 1, 2020·Current Gastroenterology Reports·Irina M CazacuManoop S Bhutani
Oct 8, 2020·Clinical Endoscopy·Jun Seong HwangTae Jun Song
Sep 21, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·John M DeWittUNKNOWN AGA Center for GI Innovation and Technology
Dec 18, 2020·Frontiers in Oncology·Vincenza GranataFrancesco Izzo
Mar 2, 2021·Frontiers in Medicine·Muhammad Nadeem YousafFizah S Chaudhary
Feb 21, 2021·Seminars in Oncology·Alberto LarghiGiampaolo Tortora
Jun 3, 2021·International Journal of Environmental Research and Public Health·Vincenza GranataFrancesco Izzo
Jun 25, 2021·World Journal of Gastroenterology : WJG·Vincenza GranataFrancesco Izzo
Sep 3, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Van Gia TruongHyun Wook Kang

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