Initial experience with SphinKeeper™ intersphincteric implants for faecal incontinence in the UK: a two-centre retrospective clinical audit.

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
C A LeoP Giordano

Abstract

The SphinKeeper™ artificial bowel sphincter implant is a relatively new surgical technique for the treatment of refractory faecal incontinence. This study presents the first experience in two UK tertiary centres. This is a retrospective audit of prospectively collected clinical data in relation to technique, safety, feasibility and short-term effectiveness from patients undergoing surgery from January 2016 to April 2019. Baseline data, intra-operative and postoperative complications, symptoms [using St Mark's incontinence score (SMIS)] and radiological outcomes were analysed. Twenty-seven patients [18 women, median age 57 years (range 27-87)] underwent SphinKeeper. In 30% of the patients, the firing device jammed and not all prostheses were delivered. There were no intra-operative complications and all patients were discharged the same or the following day. SMIS significantly improved from baseline [median -6 points (range -12 to +3); P < 0.00016] with 14/27 (51.9%) patients achieving a 50% reduction in the SMIS score. On postoperative imaging, a median of seven prostheses (range 0-10) were identified with a median of five (range 0-10) optimally placed. There was no relationship between number of well-sited prostheses on postop...Continue Reading

References

Apr 1, 1989·The British Journal of Surgery·M R KeighleyN J Mortensen
Aug 1, 1997·Diseases of the Colon and Rectum·J M DevesaJ M Enríquez
Jul 15, 1999·Journal of the American Geriatrics Society·R O RobertsN J Talley
May 30, 2003·International Journal of Colorectal Disease·H OrtizJ V Roig
Feb 24, 2004·Gastroenterology·Christine Norton
Aug 20, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J R F HollingsheadC J Vaizey
Sep 20, 2011·The British Journal of Surgery·C RattoP Giordano
Apr 4, 2012·Diseases of the Colon and Rectum·Anil T GeorgeCarolynne J Vaizey
Aug 3, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ivo DitahLawrence Szarka
Mar 19, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E V CarringtonS M Scott
May 20, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A MellgrenUNKNOWN Nasha Dx Study Group
Jan 22, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Y MaedaUNKNOWN European SNS Bowel Study Group
Sep 10, 2015·Revista da Escola de Enfermagem da U S P·Kelly Cristina Strazzieri-PulidoVera Lúcia Conceição de Gouveia Santos
Nov 7, 2015·Diseases of the Colon and Rectum·Kheng-Seong NgMarc A Gladman
Dec 15, 2015·Techniques in Coloproctology·C RattoA Parello
Jul 25, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C A LeoC J Vaizey
Apr 11, 2018·Nature Reviews. Gastroenterology & Hepatology·Emma V CarringtonUNKNOWN International Anorectal Physiology Working Group and the International Working Group for Disorders of Gastrointestinal Motil
Feb 17, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C A LeoC J Vaizey
Aug 3, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M La TorreI Clementi
Feb 18, 2020·The British Journal of Surgery·F LittaC Ratto

❮ Previous
Next ❯

Citations

Jan 10, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Christopher DawoudStefan Riss

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

© 2021 Meta ULC. All rights reserved