Abstract
A high glucose content in peritoneal dialysis (PD) solution may result in unfavorable changes on peritoneal character and worsened metabolic profiles. We conducted this retrospective cohort analysis to investigate the impact of initial glucose load on long-term outcomes of PD patients. A total of 90 patients newly started on PD were enrolled. All subjects were divided into low, medium, or high glucose load equally in patient number according to the average dialysate glucose concentration prescribed in the first 6 months from PD initiation. Cox's regression was used for survival analyses and linear regression was used for analyses of determinants for glucose load. The mean follow-up period was 40.1 +/- 11.8 months. Patients with higher glucose load showed a significantly worse cumulative technique survival (log rank p = 0.002). In Cox's regression analysis, patients with lower glucose load had significantly better technique survival (p = 0.035). In linear regression analysis, preexisting diabetes mellitus (p < 0.001), lower serum albumin (p = 0.012), and lower weekly renal Kt/V (p = 0.019) were significantly correlated with higher glucose load. Higher glucose load during the initial period of PD was associated with higher preval...Continue Reading
Citations
Apr 18, 2013·Wiener medizinische Wochenschrift·Andreas Vychytil
Oct 14, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yu-Sen PengWang-Yu Chen
Jul 15, 2009·Néphrologie & thérapeutique·J-P RyckelynckB Hurault de Ligny
Feb 18, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Moniek W M van de LuijtgaardenKitty J Jager
Feb 4, 2012·PloS One·Hon-Yen WuKwan-Dun Wu
Mar 8, 2013·PloS One·Szu-Ying LeeJenq-Wen Huang
Aug 27, 2013·PloS One·Jenq-Wen HuangKuan-Yu Hung
Dec 24, 2013·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J-W HuangK-Y Hung
Jun 29, 2012·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Thiane Gama-AxelssonAbdul Rashid Qureshi
Oct 1, 2009·Current Therapeutic Research, Clinical and Experimental·Pornanong AramwitOuppatham Supasyndh
Aug 5, 2015·Scientific Reports·Li-chun HoKuan-Yu Hung
Aug 4, 2018·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Chinakorn SujimongkolSupannee Promthet
Sep 6, 2018·PloS One·Hon-Yen WuHsien-Ching Chiu
Aug 31, 2013·Journal of the American Society of Nephrology : JASN·Rajnish Mehrotra, Ian H de Boer
Feb 12, 2017·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Samuel ChanDavid W Johnson
May 28, 2016·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Matthew B Rivara, Rajnish Mehrotra
Dec 3, 2013·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Yueqiang WenXueqing Yu
Mar 17, 2010·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Hon-Yen WuTun-Jun Tsai
Oct 1, 2013·Current Opinion in Nephrology and Hypertension·Rajnish MehrotraJonathan Himmelfarb
May 13, 2018·Basic & Clinical Pharmacology & Toxicology·Bo La HanCaigan Du