Initial Glycemic Control and Care Among Younger Adults Diagnosed With Type 2 Diabetes.

Diabetes Care
A GopalanR W Grant

Abstract

The prevalence of type 2 diabetes is increasing among adults under age 45. Onset of type 2 diabetes at a younger age increases an individual's risk for diabetes-related complications. Given the lasting benefits conferred by early glycemic control, we compared glycemic control and initial care between adults with younger onset (21-44 years) and mid-age onset (45-64 years) of type 2 diabetes. Using data from a large, integrated health care system, we identified 32,137 adults (aged 21-64 years) with incident diabetes (first HbA1c ≥6.5% [≥48 mmol/mol]). We excluded anyone with evidence of prior type 2 diabetes, gestational diabetes mellitus, or type 1 diabetes. We used generalized linear mixed models, adjusting for demographic and clinical variables, to examine differences in glycemic control and care at 1 year. Of identified individuals, 26.4% had younger-onset and 73.6% had mid-age-onset type 2 diabetes. Adults with younger onset had higher initial mean HbA1c values (8.9% [74 mmol/mol]) than adults with onset in mid-age (8.4% [68 mmol/mol]) (P < 0.0001) and lower odds of achieving an HbA1c <7% (<53 mmol/mol) 1 year after the diagnosis (adjusted odds ratio [aOR] 0.70 [95% CI 0.66-0.74]), even after accounting for HbA1c at diagnosi...Continue Reading

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Citations

Jan 28, 2021·Journal of General Internal Medicine·Anjali GopalanRichard W Grant
Dec 19, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Katherine E GoodmanAnthony D Harris
Jun 26, 2021·Diabetes Research and Clinical Practice·Fu-Shun YenChii-Min Hwu

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