Initial in-hospital heart rate is associated with three-month functional outcomes after acute ischemic stroke.

BMC Neurology
Ya-Wen KuoJiann-Der Lee

Abstract

Increased heart rate (HR) has been associated with stroke risk and outcomes. We analyzed 1,420 patients from a hospital-based stroke registry with acute ischemic stroke (AIS). Mean initial in-hospital HR and the coefficient of variation of HR (HR-CV) were derived from the values recorded during the first 3 days of hospitalization. The study outcome was the 3-month functional outcome. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using multivariable logistic regression analysis. A higher mean HR level was significantly and continuously associated with a higher probability of unfavorable functional outcomes. Compared with the reference group (mean HR < 70 beats per minute), the multivariate-adjusted OR for an unfavorable outcome was 1.81 (95% CI, 1.25-2.61) for a mean HR ≥ 70 and < 80 beats per minute, 2.52 (95% CI, 1.66 - 3.52) for a mean HR ≥ 80 and < 90 beats per minute, and 3.88 (95% CI, 2.20-6.85) for mean HR ≥ 90 beats per minute. For stroke patients with a history of hypertension, the multivariate-adjusted OR for patients with a HR-CV ≥ 0.12 (versus patients with a HR-CV < 0.08 as a reference) was 1.73 (95% CI, 1.11-2.70) for an unfavorable outcome. Our results indicated that a high initial in-hospit...Continue Reading

References

May 1, 1988·Stroke; a Journal of Cerebral Circulation·J C van SwietenJ van Gijn
Jun 1, 1987·American Heart Journal·W B KannelL A Cupples
Sep 22, 2005·Neurocritical Care·Arunodaya R GujjarNithyananda Pradhan
Dec 6, 2007·Drugs·Michael Böhm, Jan-Christian Reil
Jul 18, 2009·Journal of Neurology·H M den HertogUNKNOWN PAIS investigators
Apr 9, 2011·Stroke; a Journal of Cerebral Circulation·Janne M VeerbeekMartijn W Heymans
Jul 26, 2011·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tsong-Hai LeeUNKNOWN Chang Gung Medical System Stroke Registry Group
Nov 18, 2011·JAMA : the Journal of the American Medical Association·Bruce OvbiageleUNKNOWN PROFESS Investigators
May 9, 2013·Stroke; a Journal of Cerebral Circulation·Ralph L SaccoUNKNOWN Council on Nutrition, Physical Activity and Metabolism
Jun 12, 2013·Journal of Hypertension·Beata GraffKrzysztof Narkiewicz
Jul 23, 2014·International Journal of Cardiology·Hebun ErdurChristian H Nolte
Oct 12, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Else Charlotte SandsetTsushung A Hua
Sep 2, 2015·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Giulia OgliariBehnam Sabayan
Jan 23, 2016·Journal of the American Heart Association·Natalia S RostUNKNOWN Global Comparators Stroke GOAL collaborators
Feb 11, 2016·International Journal of Stroke : Official Journal of the International Stroke Society·Han-Gil JeongByung-Woo Yoon
May 25, 2016·Stroke; a Journal of Cerebral Circulation·Amber L Fyfe-JohnsonRichard F MacLehose
Dec 3, 2016·BMC Neurology·Marjolein GeurtsUNKNOWN DUST investigators
May 10, 2017·Materia Socio-medica·Amina NakicevicLejla Alajbegovic
Jun 9, 2017·Journal of Stroke·Keun-Sik Hong
Dec 6, 2017·Journal of Neurosciences in Rural Practice·Bhupendra ShahGunaraj Poudel
May 20, 2018·Brain and Behavior·Johan-Emil BagerBjorn Andersson
Apr 9, 2019·The Journal of Clinical Hypertension·Simona LattanziMauro Silvestrini
Sep 21, 2019·Stroke; a Journal of Cerebral Circulation·Adam de HavenonNatalia Rost

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