Initial performance evaluation of a preclinical PET scanner available as a clip-on assembly in a sequential PET/MRI system

Physics in Medicine and Biology
J M VrigneaudF Brunotte

Abstract

We evaluated the performance characteristics of a prototype preclinical PET scanner available as an easy clippable assembly that can dock to an MRI system. The single ring version of the PET system consists of eight detectors, each of which comprises a 12  ×  12 silicon photomultipliers (SiPMs) array coupled with a dual layer of offset scintillation crystals to measure depth of interaction. The crystal arrays have 29  ×  29 (30  ×  30 for the outer layer) 4 mm long LYSO crystals (6 mm for the outer layer). The ring diameter is 119.2 mm and the axial field of view is 50.4 mm. The NEMA NU 4-2008 protocol was followed for studying the PET performance. Temperature stability of SiPMs was also investigated. The peak system absolute sensitivity was 4.70% with an energy window of 250-750 keV. The spatial resolution was 1.28/1.88/1.85 mm FWHM (radial/tangential/axial) at a distance of 5 mm from the center. Peak noise equivalent counting rate and scatter fraction for mouse phantom were 61.9 kcps at 14.9 MBq and 21.0%, respectively. The uniformity was 6.3% and the spill-over ratios in the images of the water-and air-filled chambers were 0.07 and 0.17, respectively. Recovery coefficients ranged from 0.13 to 0.96. Change in sensitivity as a...Continue Reading

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Citations

Mar 13, 2019·Physics in Medicine and Biology·Devin J Van ElburgAndrew L Goertzen
Aug 27, 2019·Medical Physics·Mahsa AmirrashediMohammad Reza Ay
Dec 7, 2018·Physics in Medicine and Biology·Aaron R SelfridgeMartin S Judenhofer
Feb 12, 2021·Physics in Medicine and Biology·Youfang LaiJunwei Du
Jan 8, 2021·Physics in Medicine and Biology·Émilie GaudinRoger Lecomte
Aug 10, 2020·PET Clinics·Mahsa AmirrashediMohammad Reza Ay
Oct 20, 2021·Physics in Medicine and Biology·Han Gyu KangTaiga Yamaya

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