Initial ratings of different types of e-cigarettes and relationships between product appeal and nicotine delivery

Psychopharmacology
Peter HajekHayden McRobbie

Abstract

Little is known about features of e-cigarettes (EC) that facilitate or hinder the switch from smoking to vaping. We tested eight brands of EC to determine how nicotine delivery and other product characteristics influence user's initial reactions. Fifteen vapers tested each product after overnight abstinence from both smoking and vaping. At each session, participant's vaped ad lib for 5 min. Blood samples were taken at baseline and at 2, 4, 6, 8, 10 and 30 min after starting vaping. Participants rated the products on a range of characteristics. The products tested included six 'cig-a-like' and two refillable products, one with variable voltage. We also tested participants' own EC. All products significantly reduced urges to smoke. Refillable products delivered more nicotine and received generally superior ratings in terms of craving relief, subjective nicotine delivery, throat hit and vapour production but in overall ratings, they were joined by a cig-a-like, Blu. Participants puffed more on low nicotine delivery products. Participants' estimates of nicotine delivery from different EC were closely linked to 'throat hit'. Nicotine delivery was less important in the initial product ratings than draw resistance, mouthpiece comfort ...Continue Reading

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Citations

Jan 31, 2019·The New England Journal of Medicine·Peter HajekHayden J McRobbie
May 19, 2020·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jennifer L PearsonDavid B Abrams
Jun 28, 2020·Neuropharmacology·Asti JacksonSuchitra Krishnan-Sarin
Apr 19, 2021·Population Health Metrics·David T LevyRafael Meza
May 14, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Anna Phillips-WallerPeter Hajek
Jun 5, 2020·Neuropharmacology·Theresa Patten, Mariella De Biasi
Aug 28, 2021·International Journal of Environmental Research and Public Health·Melinda PénzesRóbert Urbán
Dec 18, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Deniz BagdasNii A Addy
Dec 12, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nicholas FelicioneMelissa D Blank

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