Initial validation of symptom scores derived from the orthostatic discriminant and severity scale.

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
Jacquie BakerKurt Kimpinski

Abstract

To develop a scale to quantify and discriminate orthostatic from non-orthostatic symptoms. In the current study, we present validation and reliability of orthostatic and non-orthostatic symptom scores taken from the orthostatic discriminate and severity scale (ODSS). Validity and reliability were assessed in participants with and without orthostatic intolerance. Convergent validity was assessed by correlating symptoms scores with previously validated tools [autonomic symptom profile (ASP) and the orthostatic hypotension questionnaire (OHQ)]. Clinical validity was assessed by correlating scores against standardized autonomic testing. Test-retest reliability was calculated using an intra-class correlation coefficient. Convergent validity: orthostatic (OS) and non-orthostatic (NS) symptom scores from 77 controls and 67 patients with orthostatic intolerance were highly correlated with both the orthostatic intolerance index of the ASP (OS: r = 0.903; NS: r = 0.651; p < 0.001) and the composite score of the OHQ: (OS: r = 0.800; NS: r = 0.574; p < 0.001). Clinical validity: symptom scores were significantly correlated with the total composite autonomic severity score (OS: r = 0.458; NS: r = 0.315; p < 0.001), and the systolic blood pr...Continue Reading

References

Oct 15, 1998·Journal of the Royal Society of Medicine·K M Bleasdale-Barr, C J Mathias
Jun 14, 2000·Circulation·J R ShannonI Biaggioni
Apr 17, 2004·Seminars in Neurology·Phillip A Low
Apr 23, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Phillip A Low
Jun 3, 2010·Mayo Clinic Proceedings·Kurt KimpinskiPhillip A Low
Mar 25, 2011·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Roy FreemanJ Gert van Dijk
Nov 3, 2011·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Horacio KaufmannRoy Freeman
Jul 17, 2012·Mayo Clinic Proceedings·Kurt KimpinskiPhillip A Low

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Jan 4, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Jacquie BakerKurt Kimpinski

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