Injection pharyngoplasty with calcium hydroxylapatite for velopharyngeal insufficiency: patient selection and technique

Archives of Otolaryngology--head & Neck Surgery
Matthew T BriggerChristopher J Hartnick

Abstract

To identify children who may benefit from calcium hydroxylapatite (CaHA) injection pharyngoplasty for symptomatic velopharyngeal insufficiency (VPI). Retrospective review of children with VPI who underwent injection pharyngoplasty with CaHA. Multidisciplinary pediatric aerodigestive center. Children with symptomatic VPI as defined by abnormal speech associated with subjective and objective measures of hypernasality. Posterior pharyngeal wall augmentation with injectable CaHA. Nasalence scores recorded as number of standard deviations (SDs) from normalized scores, and perceptual scoring recorded as standardized weighted score and caretaker satisfaction from direct report. Twelve children who had undergone injection pharyngoplasty with CaHA were identified. Of the 12 children, 8 demonstrated success at 3 months as defined by nasalence (<1 SD above normal nasalance scores), perceptual scoring (decrease in weighted score), and overall caretaker satisfaction. Four children were followed up for more than 24 months and continued to demonstrate stable success. The 4 children who failed the procedure all failed before the 3-month evaluation and demonstrated increased baseline severity of VPI as defined by increased preoperative nasalenc...Continue Reading

Citations

Oct 5, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·A BishopM Bezuhly
Mar 13, 2014·Clinics in Plastic Surgery·Michael S Gart, Arun K Gosain
May 17, 2012·Otolaryngologic Clinics of North America·James M RudaAustin S Rose
Aug 30, 2011·International Journal of Pediatric Otorhinolaryngology·Nicolas LeboulangerGarabedian Eréa-Noël
Jan 19, 2012·The Laryngoscope·Stefan W ShuaibMichael E Kupferman
Jun 29, 2015·Clinics in Plastic Surgery·Riccardo F MazzolaIsabella C Mazzola
Feb 27, 2014·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Ashley G O'ReillyShelagh A Cofer
Jul 30, 2019·Otolaryngologic Clinics of North America·Brandon HopkinsAmelia F Drake
Mar 9, 2021·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Colin FullerLarry Hartzell
May 7, 2021·International Journal of Pediatric Otorhinolaryngology·Rebecca BellAlexander P Marston
Jul 31, 2021·International Journal of Pediatric Otorhinolaryngology·Elton M LambertTara L Rosenberg
Sep 19, 2018·Mayo Clinic Proceedings. Innovations, Quality & Outcomes·Brandon W PeckShelagh A Cofer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Otolaryngology--head & Neck Surgery
J Andrew SippChristopher J Hartnick
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Yimei CaoZhenmin Zhao
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Igor LeuchterPhilippe Pasche
© 2021 Meta ULC. All rights reserved