Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction?

European Heart Journal
Matthias Nahrendorf, Filip K Swirski

Abstract

Knowledge of macrophages in steady-state and diseased tissue is rapidly expanding, propelled by improved diagnostic capacity to detect and monitor cells in their native environments. In this review, we discuss implications for ischaemic heart disease and examine innate immune cell pathways that increase systemic leucocyte supply after myocardial infarction (MI). Acute MI alters the macrophage phenotype and supply chain from tissue resident to blood monocytes sourced from haematopoietic organs. That blood leucocytosis closely associates with cardiovascular mortality provides a strong motivation to understand why and how organ ischaemia alters cellular immunity.

References

May 1, 1987·JAMA : the Journal of the American Medical Association·E ErnstJ A Dormandy
Sep 28, 2000·The New England Journal of Medicine·J A GoldsteinW W O'Neill
Jan 4, 2007·The Journal of Clinical Investigation·Filip K SwirskiMikael J Pittet
Nov 21, 2007·The Journal of Experimental Medicine·Matthias NahrendorfMikael J Pittet
Jul 29, 2008·International Journal of Cardiology·Jessica M LambertMerry L Lindsey
Feb 18, 2009·The Journal of Experimental Medicine·Jae-Hoon ChoiRalph M Steinman
Sep 1, 2009·The New England Journal of Medicine·Lars WallentinMona Thorsén
Sep 16, 2009·The Journal of Experimental Medicine·Su-Ning ZhuMyron I Cybulsky
Oct 8, 2009·Circulation. Heart Failure·Gunnar EngströmBo Hedblad
Feb 6, 2010·Science·Frederic GeissmannKlaus Ley
Mar 16, 2011·The Journal of Experimental Medicine·Armin Ehninger, Andreas Trumpp
Jul 26, 2011·The New England Journal of Medicine·John H AlexanderUNKNOWN APPRAISE-2 Investigators
Nov 15, 2011·The New England Journal of Medicine·Jessica L MegaUNKNOWN ATLAS ACS 2–TIMI 51 Investigators
Nov 15, 2011·The New England Journal of Medicine·Matthew T Roe, E Magnus Ohman
Jan 4, 2012·The Journal of Experimental Medicine·Florian LeuschnerMatthias Nahrendorf
Jul 6, 2012·Nature·Partha DuttaMatthias Nahrendorf
Jan 12, 2013·Science·Filip K Swirski, Matthias Nahrendorf
May 15, 2013·Cell Metabolism·Prabhakara R NagareddyIra J Goldberg
Jun 8, 2013·Circulation Research·Matthias Nahrendorf, Filip K Swirski
Aug 13, 2013·Nature Medicine·Clinton S RobbinsFilip K Swirski
Sep 26, 2013·Proceedings of the National Academy of Sciences of the United States of America·Nicole D PowellSteven W Cole
Jan 15, 2014·The International Journal of Cardiovascular Imaging·Yunfeng HanYundai Chen
Jan 17, 2014·Nature·Sean J Morrison, David T Scadden
Mar 26, 2014·Nature Reviews. Cardiology·Nikolaos G Frangogiannis
May 9, 2014·Cell Metabolism·Prabhakara R NagareddyAndrew J Murphy
May 24, 2014·Nature Reviews. Immunology·Florent Ginhoux, Steffen Jung
Jun 24, 2014·Nature Medicine·Timo HeidtMatthias Nahrendorf
Aug 8, 2014·Nature Medicine·Avital Mendelson, Paul S Frenette

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Citations

Mar 16, 2016·European Heart Journal·Thomas F Lüscher
Apr 16, 2016·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Daniela Carnevale, Giuseppe Lembo
Apr 27, 2016·Seminars in Immunology·Anette ChristNiels P Riksen
Aug 11, 2016·Frontiers in Immunology·Zarah BatulanEdward R O'Brien
Nov 12, 2016·Biochimica Et Biophysica Acta. Molecular Cell Research·Yvan Devaux
Apr 21, 2018·Stem Cells·Conrad P HodgkinsonVictor J Dzau
Sep 12, 2017·European Journal of Heart Failure·Yingying ZhangHarald F Langer
Sep 17, 2016·Circulation Research·Karen Patterson
Oct 9, 2018·Cardiovascular Research·Maximilian J SchlossSabine Steffens
Oct 12, 2018·Cardiovascular Research·Kotaro MatsumotoYasushi Fujio
Apr 10, 2020·Circulation Research·Wolfram C PollerFilip K Swirski
Jun 7, 2019·Nature Reviews. Disease Primers·Birgit VogelRoxana Mehran
Mar 3, 2017·Pflügers Archiv : European journal of physiology·Manfred NairzGuenter Weiss
May 4, 2017·Mediators of Inflammation·Daniel P JonesJyoti Patel
May 23, 2017·European Heart Journal·Thomas F Lüscher
May 8, 2020·Cardiology Research and Practice·Sophia Esi DuncanGuanwei Fan
Jul 2, 2017·Current Heart Failure Reports·Sophie Van Linthout, Carsten Tschöpe
Dec 14, 2018·Basic Research in Cardiology·Mira JungThomas Thum
Feb 9, 2019·Experimental Biology and Medicine·David H Wu, Antonis K Hatzopoulos
Dec 8, 2020·Frontiers in Cell and Developmental Biology·Kikkie PoelsJeffrey Kroon
Apr 4, 2021·International Journal of Molecular Sciences·Iwona ŚwiątkiewiczJacek Kubica

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