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Innate immunity in Alzheimer's disease: a complex affair

CNS & Neurological Disorders Drug Targets

Apr 12, 2013

Marie-Victoire Guillot-Sestier, Terrence Town

PMID: 23574177

Abstract

Alzheimer's disease (AD) is characterized by three major histopathological hallmarks: β-amyloid deposits, neurofibrillary tangles and gliosis. While neglected for decades, the neuroinflammatory processes coordinated by microglia are now accepted as etiologic events in AD evolution. Micr...read more

Mentioned in this Paper

Familial Alzheimer Disease (FAD)
APP protein, human
Neurofibrillary Degeneration (Morphologic Abnormality)
Brain
Plaque, Amyloid
Entire Central Nervous System
Alzheimer's Disease
Chemokine
Amyloid Deposition
Diffuse Neurofibrillary Tangles With Calcification
Paper Details
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Innate immunity in Alzheimer's disease: a complex affair

CNS & Neurological Disorders Drug Targets

Apr 12, 2013

Marie-Victoire Guillot-Sestier, Terrence Town

PMID: 23574177

DOI:

Abstract

Alzheimer's disease (AD) is characterized by three major histopathological hallmarks: β-amyloid deposits, neurofibrillary tangles and gliosis. While neglected for decades, the neuroinflammatory processes coordinated by microglia are now accepted as etiologic events in AD evolution. Micr...read more

Mentioned in this Paper

Familial Alzheimer Disease (FAD)
APP protein, human
Neurofibrillary Degeneration (Morphologic Abnormality)
Brain
Plaque, Amyloid
Entire Central Nervous System
Alzheimer's Disease
Chemokine
Amyloid Deposition
Diffuse Neurofibrillary Tangles With Calcification

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Paper Details
References
  • References
  • Citations36
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations36
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