Innate lymphocytes-lineage, localization and timing of differentiation.

Cellular & Molecular Immunology
Emily R Kansler, Ming O Li

Abstract

Innate lymphocytes are a diverse population of cells that carry out specialized functions in steady-state homeostasis and during immune challenge. While circulating cytotoxic natural killer (NK) cells have been studied for decades, tissue-resident innate lymphoid cells (ILCs) have only been characterized and studied over the past few years. As ILCs have been largely viewed in the context of helper T-cell biology, models of ILC lineage and function have been founded within this perspective. Notably, tissue-resident innate lymphocytes with cytotoxic potential have been described in an array of tissues, yet whether they are derived from the NK or ILC lineage is only beginning to be elucidated. In this review, we aim to shed light on the identities of innate lymphocytes through the lenses of cell lineage, localization, and timing of differentiation.

References

May 15, 2002·Nature Immunology·Sungjin KimWayne M Yokoyama
Feb 15, 2003·Blood·Thomas RansonJames P Di Santo
Nov 13, 2004·Science·Dapeng ZhouAlbert Bendelac
Jan 22, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Christian A J VosshenrichJames P Di Santo
Mar 18, 2005·Annual Review of Immunology·Mitchell Kronenberg
Sep 1, 2005·The Journal of Experimental Medicine·Mark J SmythYoshihiro Hayakawa
Nov 8, 2005·Nature Immunology·Andrew M IntlekoferSteven L Reiner
Sep 14, 2006·Development·Hanna K A Mikkola, Stuart H Orkin
Nov 15, 2006·Immunological Reviews·Wayne M Yokoyama, Sungjin Kim
Mar 7, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yein-Gei LaiNan-Shih Liao
Apr 22, 2008·Nature Immunology·Lewis L Lanier
Feb 10, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Gili G HalfteckOfer Mandelboim
Jun 26, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Lisa J MaKimberly S Schluns
Jul 25, 2009·Nature Reviews. Immunology·David H Raulet, Nadia Guerra
Feb 9, 2010·Nature Immunology·Dale I GodfreyAlan G Baxter
Feb 10, 2010·The Journal of Experimental Medicine·Naoko Satoh-TakayamaJames P Di Santo
Mar 5, 2010·Nature·Daniel R NeillAndrew N J McKenzie
Jun 23, 2010·Immunology and Cell Biology·Hollie J PegramMichael H Kershaw
Jun 18, 2011·Nature Reviews. Immunology·Hilde CheroutreDaniel Mucida
Aug 27, 2011·Nature Reviews. Immunology·Joseph C Sun, Lewis L Lanier
Jan 24, 2012·Nature Immunology·See Heng WongAndrew N J McKenzie
Feb 7, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ariella GlasnerOfer Mandelboim
Jan 26, 2013·Nature Reviews. Immunology·Hergen SpitsEric Vivier
Mar 26, 2013·The Journal of Clinical Investigation·Hui PengZhigang Tian
Sep 24, 2013·Trends in Immunology·Jianhua YuMichael A Caligiuri
Oct 29, 2013·Nature Immunology·Laura K MackayThomas Gebhardt
Nov 23, 2013·European Journal of Microbiology & Immunology·Andreas Diefenbach
Feb 11, 2014·Nature·Michael G ConstantinidesAlbert Bendelac

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Citations

Nov 12, 2019·International Journal of Cancer. Journal International Du Cancer·Lu QiFang Fang
Dec 6, 2019·Journal of Leukocyte Biology·Gang XuZheng Zhang
Nov 30, 2019·Clinical Reviews in Allergy & Immunology·Chao HuangZhigang Tian
Aug 28, 2020·Frontiers in Immunology·Jiacheng Bi, Xuefu Wang
Sep 29, 2020·Frontiers in Immunology·Jingjing Cong
Aug 9, 2020·Frontiers in Immunology·Yongyan Chen, Zhigang Tian
Jul 17, 2020·Frontiers in Immunology·Hua-Xing WeiBofeng Li
Oct 13, 2020·Frontiers in Immunology·Lu Li, Zhutian Zeng
Oct 20, 2020·Frontiers in Immunology·Xunyao Wu

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