Inner retinal vasculopathy in Zika virus disease

American Journal of Ophthalmology Case Reports
Mandeep S SinghWilliam N May

Abstract

Zika virus infection is associated with vision-threatening ocular complications including uveitis and outer retinopathy. The aim of this report is to describe a case of an adult patient with serologically confirmed Zika infection who presented with retinal vascular abnormalities that coincided with systemic post-viral neurological manifestations of the disease. A 34-year-old white female presented with symptoms of peripheral neuropathy following serologically confirmed Zika virus infection that was acquired in Puerto Rico four months prior to presentation. Ocular evaluation revealed perifoveal microaneurysms which were not associated with visual symptoms. These data potentially expand the phenotypic spectrum of Zika virus retinopathy. In addition to outer retinal abnormalities which are well-described in infants and adults, inner retinal vascular abnormalities may also occur and may be temporally associated with post-viral neurological sequelae of Zika virus infection. Clinicians should be aware of potential retinal involvement in affected patients who present with neurological symptoms after recovery from acute Zika virus infection.

Citations

Jul 4, 2018·Ocular Immunology and Inflammation·Emmett T CunninghamManfred Zierhut
Oct 1, 2019·Ocular Immunology and Inflammation·Paulo JimenezAndré Luiz Land Curi
Aug 23, 2020·Indian Journal of Ophthalmology·Padmamalini MahendradasMoncef Khairallah
Nov 26, 2020·JAMA Ophthalmology·Yacine TroumaniLaurence Beral
Oct 24, 2020·International Ophthalmology Clinics·Camila V VenturaLiana O Ventura

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