Innervation asymmetry of the external anal sphincter in aging characterized from high-density intra-rectal surface EMG recordings

Neurourology and Urodynamics
Nicholas DiasYingchun Zhang

Abstract

The innervation zone asymmetry of the external anal sphincter (EAS) has been investigated as a risk factor for the development of fecal incontinence (FI). This study aims to utilize an intra-rectal high-density surface electromyogram (HD-sEMG) recording and advanced HD-sEMG decomposition technique to characterize the effects of aging on the asymmetry of EAS functional innervation. HD-sEMG signals were recorded intra-rectally from six healthy young and seven healthy elderly women during voluntary contractions of the EAS. EMG signals were decomposed into constituent motor unit action potentials (MUAPs) and the innervation zone of each decomposed motor unit was identified. Asymmetry index (AI) was defined and calculated for all subjects. The maximum squeezing pressures of the EAS were also measured for all subjects as a comparison. The HD-sEMG decomposition and AI calculation were successfully performed from EMG data acquired from all the subjects. The AI values were 28.7 ± 17.0% for the young group and 55.6 ± 18.8% for the elderly group. The AI and EAS contraction strength were found to be negatively correlated (P < 0.05). A two-tailed student's t-test demonstrated a significant increase in AI with age by comparison between two g...Continue Reading

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Citations

Jul 20, 2019·Neurourology and Urodynamics·Nicholas DiasYingchun Zhang
Mar 15, 2019·Journal of Neural Engineering·Chuan ZhangYingchun Zhang
Mar 14, 2019·International Urogynecology Journal·Xuhong LiYingchun Zhang
Mar 27, 2020·The Journal of International Medical Research·Bo YaoJiangbo Pu
Aug 8, 2020·International Urogynecology Journal·Nicholas DiasYingchun Zhang

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