Innervation in women with uterine myoma and adenomyosis

Obstetrics & Gynecology Science
Ye Jin ChoiJae Whoan Koh

Abstract

To determine if neurofilament (NF) is expressed in the endometrium and the lesions of myomas and adenomyosis, and to determine their correlation. Histologic sections were prepared from hysterectomies performed on women with adenomyosis (n=21), uterine myoma (n=31), and carcinoma in situ of the uterine cervix. Full-thickness uterine paraffin blocks, which included the endometrium and myometrium histologic sections, were stained immunohistochemically using the antibodies for monoclonal mouse antihuman NF protein. NF-positive cells were found in the endometrium and myometrium in 11 women with myoma and in 7 with adenomyosis, but not in patients with carcinoma in situ of uterine cervix, although the difference was statistically not significant. There was no significant difference between the existence of NF-positive cells and menstrual pain or phases. The NF-positive nerve fibers were in direct contact with the lesions in nine cases (29.0%) of myoma and in five cases (23.8%) of adenomyosis. It was analyzed if there was a statistical significance between the existence of NF positive cells in the endometrium and the expression of NF-positive cells in the uterine myoma/adenomyosis lesions. When NF-positive cell were detected in the my...Continue Reading

References

Nov 1, 1989·Journal of Neurochemistry·R GonzalesJ D Levine
Jun 28, 2000·The Clinical Journal of Pain·S C Apfel
Aug 16, 2001·Annals of Surgery·H SulaimanS E Herrick
Jul 13, 2002·Annals of the New York Academy of Sciences·Hans-Georg SchaibleGisela Segond Von Banchet
Jan 9, 1959·Annals of the New York Academy of Sciences·K E KRANTZ
Dec 12, 2003·Fertility and Sterility·Sheri A LippmanBrenda Eskenazi
Nov 2, 2005·American Journal of Obstetrics and Gynecology·Gurprit AtwalMartin Quinn
Mar 1, 2006·Obstetrics and Gynecology Clinics of North America·Orhan Bukulmez, Kevin J Doody
Sep 5, 2006·Human Reproduction·Natsuko TokushigeIan S Fraser
Sep 30, 2006·Fertility and Sterility·Vincent AnafJean-Christophe Noël
Apr 3, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S KisslerM Kaufmann
Apr 28, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M Quinn
Jun 19, 2009·Fertility and Sterility·Xinmei ZhangJun Lin
Aug 7, 2009·Acta Obstetricia Et Gynecologica Scandinavica·Melissa G Medina, Dan I Lebovic

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Citations

Oct 9, 2020·Seminars in Reproductive Medicine·Junyu ZhaiLinda C Giudice
Feb 20, 2021·Reproductive Biology and Endocrinology : RB&E·Xiaofang XuSun-Wei Guo

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Methods Mentioned

BETA
hysterectomy

Software Mentioned

SAS

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