Innervation of adult human laryngeal muscle fibers

Journal of the Neurological Sciences
S PériéA Sebille

Abstract

The innervation of laryngeal muscle fibers was appraised in adult humans. Sixteen intrinsic laryngeal muscles were dissected during the autopsy of 4 adults (41-71 years old). Longitudinal serial frozen sections, 60 microm thick, of the whole muscles were double-stained for cholinesterase activity and axonal visualization. About 945 endplates per muscle were analysed using light microscopy. The neuromuscular junctions were always scattered throughout the whole muscles. Most of the muscle fibers showed a single neuromuscular junction, but multi-innervated fibers were found in all of the muscles. Their number was highest in interarytenoid muscles (21% of all the fibers). The distance between multiple neuromuscular junctions was most frequently less than 150 microm. Two neuromuscular junctions were frequently displayed, opposite one another, particularly in thyroarytenoid muscles, and this unusual feature seems specific for laryngeal muscles. The innervation of all of the muscle fibers was exclusively found to be unineuronal, with multi-innervated fibers being innervated by a single axon. Distal axonal degeneration occurred with aging, resulting in a loss in the number of multi-innervated muscle fibers.

References

Jan 1, 1990·Progress in Neurobiology·J K Jansen, T Fladby
Jun 1, 1974·The Anatomical Record·M M SalpeterH H Feng
Jan 1, 1972·Histochemie. Histochemistry. Histochimie·J Juntunen, H Teräväinen
Mar 1, 1970·Acta Oto-laryngologica·C H HertzB Sonesson
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·H Teräväinen
Jun 1, 1966·Acta Physiologica Scandinavica·A Mårtensson
Jan 1, 1981·Annual Review of Neuroscience·M C BrownW G Hopkins
Sep 1, 1980·The Journal of Laryngology and Otology·J MoralesM Gayoso

❮ Previous
Next ❯

Citations

May 27, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Andrew BlitzerGayle E Woodson
Oct 3, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·L T MalmgrenT Uno
Feb 18, 2012·Journal of Speech, Language, and Hearing Research : JSLHR·Megan DaughertyAlan J Sokoloff
Feb 19, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Colleen A McMullen, Francisco H Andrade
Apr 3, 2010·Journal of Applied Physiology·Zoia C LatevaM Elise Johanson
May 15, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Aaron M JohnsonNadine P Connor
Nov 26, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Roberto Lagunes-CórdobaE J Muñoz-Martínez
Oct 27, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Naoya NishidaJunzo Desaki
Feb 18, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Tolga Ozdemirkiran, Cumhur Ertekin
Jan 24, 2007·Journal of Voice : Official Journal of the Voice Foundation·Lisa B ThomasJoseph C Stemple
Jan 29, 2005·Acta Physiologica Scandinavica·J F Y Hoh
Sep 29, 2006·Journal of Anatomy·Paul J Kingham, Giorgio Terenghi
Jan 29, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·B KallmünzerJ Wörl
Mar 1, 2012·The Laryngoscope·Xin FengChristy L Ludlow
Sep 14, 2016·International Journal of Pediatric Otorhinolaryngology·Janaina Gonçalves da Silva LeiteMarcos Rabelo de Freitas
Jul 20, 2002·The Annals of Otology, Rhinology, and Laryngology·Nadine P ConnorDennis M Heisey
Aug 6, 1999·The Annals of Otology, Rhinology, and Laryngology·S PériéA Sebille
Nov 27, 2002·The Annals of Otology, Rhinology, and Laryngology·Tatsutoshi SuzukiKatsuhide Inagi
May 22, 2016·Physiological Reports·Joseph C StempleColleen A McMullen
Jun 14, 2000·The Laryngoscope·N TakedaC L Ludlow
Aug 20, 2018·Muscle & Nerve·Rais ObongoJean-Paul Marie
Apr 15, 2006·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Manuel Lima-RodriguesArmando Almeida
May 29, 2008·Journal of Speech, Language, and Hearing Research : JSLHR·Lisa B ThomasJoseph C Stemple
Dec 17, 2009·Journal of Speech, Language, and Hearing Research : JSLHR·Lisa T FryFrancisco H Andrade
Nov 26, 2010·Journal of Speech, Language, and Hearing Research : JSLHR·Colleen A McMullenJoseph C Stemple
May 9, 2007·Muscle & Nerve·Alan J SokoloffThomas J Burkholder
May 2, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Gulgun KayaliogluCumhur Ertekin
Nov 8, 2020·Dysphagia·Mohammed Elrabie Ahmed MohammedHesham Mostafa Abdelfattah
May 12, 2019·Journal of Voice : Official Journal of the Voice Foundation·Lori Lombard, Nancy Pearl Solomon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.