Inophyllin A, a new pyranoxanthone from Calophyllum inophyllum (Guttiferae)

Natural Product Research
G C L EeH L Lee

Abstract

In the authors' continuing search for new natural products, their recent studies on the roots of Calophyllum inophyllum (Guttiferae) have yielded a new prenylated pyranoxanthone, Inophyllin A together with the common triterpenes friedelin and stigmasterol. Structural elucidations of these compounds were achieved through (1)H, (13)C, DEPT, COSY, HSQC and HMBC experiments. The molecular mass was determined using MS techniques. The authors report here the isolation of and structural elucidation for Inophyllin A as well as its toxicity test result. The discovery of this new natural product from the unexploited Malaysian forest will certainly contribute to the search for potential natural larvicides.

References

Feb 24, 2001·Phytochemistry·A KijjoaW Herz
Sep 29, 2001·Phytochemistry·D GuiletJ Bruneton

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Citations

Mar 22, 2016·Journal of Asian Natural Products Research·Wen-Nee TanDarah Ibrahim
May 23, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Kok Meng ChanSalmaan Hussain Inayat-Hussain
Jan 20, 2018·Natural Product Research·Sasa PonguschariyagulSanti Tip-Pyang
Mar 26, 2009·Chemistry & Biodiversity·Valdir Cechinel FilhoRivaldo Niero
Jul 18, 2020·Natural Product Research·Thiruventhan KarunakaranVivien Yi Mian Jong
Apr 17, 2021·Natural Product Research·Natalia Mendes Gomes MagalhaesLaila Salmen Espindola

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Methods Mentioned

BETA
column chromatography

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