Inorganic-binding peptides as tools for surface quality control

Journal of Inorganic Biochemistry
Christelle VreulsCécile Van de Weerdt

Abstract

This paper highlights an innovative application of inorganic-binding peptides as quality control tools for detecting defects on inorganic surfaces of any shape. The approach involves attaching a fluorescent label to an inorganic-binding peptide and exploiting the peptide's high binding specificity to detect, by simple fluorescence microscopy, chemical composition defects of microm size and crystallographic state defects. Proof of concept was demonstrated by monitoring binding of a previously isolated ZnO-binding peptide to galvanized steel substrates. The approach was further validated for TiO(2) coatings and stainless steel, with two new, specific inorganic-binding peptides isolated by phage display.

Citations

Sep 12, 2015·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Nan DuAidong Zhang
Aug 6, 2016·Physical Chemistry Chemical Physics : PCCP·A GladytzB Abel
Feb 11, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Urartu Ozgur Safak Seker, Hilmi Volkan Demir
Sep 25, 2019·Biotechnology and Bioengineering·Sarah DedischUlrich Schwaneberg

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