Inorganic polyphosphates in extremophiles and their possible functions.

Extremophiles : Life Under Extreme Conditions
Alvaro OrellCarlos A Jerez

Abstract

Many extremophilic microorganisms are polyextremophiles, being confronted with more than one stress condition. For instance, some thermoacidophilic microorganisms are in addition capable to resist very high metal concentrations. Most likely, they have developed special adaptations to thrive in their living environments. Inorganic polyphosphate (polyP) is a molecule considered to be primitive in its origin and ubiquitous in nature. It has many roles besides being a reservoir for inorganic phosphate and energy. Of special interest are those functions related to survival under stressing conditions in all kinds of cells. PolyP may therefore have a fundamental part in extremophilic microorganism's endurance. Evidence for a role of polyP in the continued existence under acidic conditions, high concentrations of toxic heavy metals and elevated salt concentrations are reviewed in the present work. Actual evidence suggests that polyP may provide mechanistic alternatives in tuning microbial fitness for the adaptation under stressful environmental situations and may be of crucial relevance amongst extremophiles. The enzymes involved in polyP metabolism show structure conservation amongst bacteria and archaea. However, the lack of a canoni...Continue Reading

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Citations

May 31, 2013·Applied Microbiology and Biotechnology·Mario VeraWolfgang Sand
Feb 2, 2013·Folia Microbiologica·Ludmila TrilisenkoIgor Kulaev
Mar 20, 2013·Archaea : an International Microbiological Journal·Alvaro OrellCarlos A Jerez
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Jan 22, 2021·FEMS Microbiology Reviews·April M LewisRobert M Kelly
Jan 23, 2021·Microorganisms·Alejandra RecaldeCarlos A Jerez
Feb 23, 2021·Extremophiles : Life Under Extreme Conditions·Carlos Eduardo BarragánDolly Montoya
Mar 16, 2021·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Thomas Glonek

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