Inpatient vs outpatient management and timing of delivery of uncomplicated monochorionic monoamniotic twin pregnancy: the MONOMONO study

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
MONOMONO Working Group

Abstract

Monoamniotic twin pregnancies are at increased risk of perinatal complications, primarily owing to the risk of cord entanglement. There is no recommendation on whether such pregnancies should be managed in hospital or can be safely managed in an outpatient setting, and the timing of planned delivery is also a subject of debate. The aim of this study was to compare the perinatal outcomes of inpatient vs outpatient fetal surveillance approaches employed among 22 participating study centers, and to calculate the fetal and neonatal death rates according to gestational age, in non-anomalous monoamniotic twins from 26 weeks' gestation. The MONOMONO study was a multinational cohort study of consecutive women with monochorionic monoamniotic twin pregnancies, who were referred to 22 university hospitals in Italy, the USA, the UK and Spain, from January 2010 to January 2017. Only non-anomalous uncomplicated monoamniotic twin pregnancies with two live fetuses at 26 + 0 weeks' gestation were included in the study. In 10 of the centers, monoamniotic twins were managed routinely as inpatients, whereas in the other 12 centers they were managed routinely as outpatients. The primary outcome was intrauterine fetal death. We also planned to asses...Continue Reading

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Citations

Aug 21, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F D'AntonioG Acharya
Oct 16, 2018·Minerva ginecologica·Rossana Di SarnoGabriele Saccone
May 28, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G SacconeUNKNOWN MONOMONO, NorSTAMP and STORK research collaboratives
Oct 9, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D MurganoF D'antonio
Feb 12, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T Van Mieghem, A Shub
Oct 16, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E LitwinskaK H Nicolaides
Nov 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Priyanka JhaAnne Kennedy
Jul 8, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D Di MascioF D'Antonio
Apr 25, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D Di MascioF D'Antonio
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May 5, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Francesco D'AntonioAsma Khalil
Aug 18, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A Khalil, B Liu
Aug 29, 2021·American Journal of Obstetrics & Gynecology MFM·Amir AviramElad Mei-Dan
Sep 27, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Amélie DelabaereDenis Gallot
Nov 4, 2021·American Journal of Obstetrics & Gynecology MFM·Tim Van MieghemGreg Ryan

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