Input and output compensation for the cochlear traveling wave delay in wide-band ABR recordings: implications for small acoustic tumor detection.

Journal of the American Academy of Audiology
Manuel DonErin Maloff

Abstract

The Stacked ABR (auditory brainstem response) attempts at the output of the auditory periphery to compensate for the temporal dispersion of neural activation caused by the cochlear traveling wave in response to click stimulation. Compensation can also be made at the input by using a chirp stimulus. It has been demonstrated that the Stacked ABR is sensitive to small tumors that are often missed by standard ABR latency measures. Because a chirp stimulus requires only a single data acquisition run whereas the Stacked ABR requires six, we try to evaluate some indirect evidence justifying the use of a chirp for small tumor detection. We compared the sensitivity and specificity of different Stacked ABRs formed by aligning the derived-band ABRs according to (1) the individual's peak latencies, (2) the group mean latencies, and (3) the modeled latencies used to develop a chirp. For tumor detection with a chosen sensitivity of 95%, a relatively high specificity of 85% may be achieved with a chirp. It appears worthwhile to explore the actual use of a chirp because significantly shorter test and analysis times might be possible.

References

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Citations

Dec 3, 2008·The Journal of the Acoustical Society of America·Claus Elberling, Manuel Don
Nov 30, 2010·The Journal of the Acoustical Society of America·Claus Elberling, Manuel Don
Oct 26, 2010·The Journal of the Acoustical Society of America·Matthew A PetoeWayne J Wilson
Mar 19, 2014·International Journal of Pediatric Otorhinolaryngology·Zheng-min XuZhi-hong Yao
Mar 27, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·K ReffetD Bakhos
May 17, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Bretislav GalErmis Vogazianos

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