Insect-malaria parasites interactions: the salivary gland

Insect Biochemistry and Molecular Biology
Mario H Rodriguez, Fidel de la C Hernández-Hernández

Abstract

Mosquito salivary glands are organs specialized in the production of a complex mix of molecules that digest carbohydrates from plant nectars, and facilitate blood feeding by the lubrication of mouthparts and the inhibition of homeostasis. Malaria sporozoites invade salivary glands and are injected with the saliva into vertebrate hosts during blood feeding. Sporozoites utilize molecules on their surface coat and outer pellicle membrane to adhere and invade specific regions of the salivary gland lobes. They transverse the secretory cells and are stored in the salivary duct, where transcription of new genes prepares them for vertebrate host invasion. Although it is probably that specific carbohydrate molecules on the surface of salivary glands function as parasites receptors, these have not been identified, neither other molecules nor mechanisms used by the parasite to invade, survive and mature within these organs. The recent advances in the sequence of the genomes of Anopheles gambiae and Plasmodium falciparum, and new developments in genomics and proteomics may help to elucidate the participating molecules, their regulation and interactions.

References

Oct 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·W O RogersS L Hoffman
Aug 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J H AdamsL H Miller
Apr 1, 1990·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·C F GolendaR A Wirtz
Jan 1, 1986·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·P A Rossignol, A M Lueders
Jul 1, 1985·The American Journal of Tropical Medicine and Hygiene·R Rosenberg
Oct 1, 1974·The Journal of protozoology·J P Vanderberg
Oct 1, 1971·Canadian Journal of Zoology·H G Janzen, K A Wright
Apr 1, 1968·Experimental Parasitology·I Schneider
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J M RibeiroA Spielman
Dec 15, 1984·Experientia·R E Sinden
Apr 1, 1983·Parasitology·R E Sinden
Jan 1, 1984·Annual Review of Biochemistry·C W Tabor, H Tabor
Jan 1, 1984·The American Journal of Tropical Medicine and Hygiene·P A RossignolA Spielman
Nov 1, 1980·The Journal of protozoology·V R Daher, A U Krettli
Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·D S PetersonT E Wellems
Jan 1, 1995·Annual Review of Entomology·W A Foster
Jan 31, 1995·Proceedings of the National Academy of Sciences of the United States of America·D E ChampagneA A James
Nov 1, 1994·The Journal of Eukaryotic Microbiology·P F PimentaL Miller
Jan 4, 1994·Proceedings of the National Academy of Sciences of the United States of America·D E Champagne, J M Ribeiro
May 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M ShahabuddinD C Kaslow
Apr 1, 1996·The American Journal of Tropical Medicine and Hygiene·J E OsorioT M Yuill
Jul 1, 1996·Journal of Medical Entomology·K R Stark, A A James
Oct 15, 1996·Proceedings of the National Academy of Sciences of the United States of America·T F McCutchanL H Miller
Feb 1, 1996·Molecular and Biochemical Parasitology·U FrevertV Nussenzweig
Apr 1, 1996·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·O MarinottiC K Moreira
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jun 6, 1998·Journal of Medical Entomology·J F EdwardsB J Beaty
Dec 22, 1999·Biochemistry·I M FrancischettiJ M Ribeiro

❮ Previous
Next ❯

Citations

Jan 8, 2013·Vector Borne and Zoonotic Diseases·Aleksandar ZocevicValérie Choumet
Apr 19, 2011·Malaria Journal·Lena Hulden, Larry Hulden
Jul 27, 2011·Journal of Insect Physiology·Rajnikant DixitArun Sharma
Feb 15, 2007·Insect Molecular Biology·F E Cázares-RagaF de la Cruz Hernández-Hernández
Aug 16, 2006·Insect Molecular Biology·S Yoshida, H Watanabe
Jul 18, 2009·Current Opinion in Microbiology·Anil Kumar Ghosh, Marcelo Jacobs-Lorena
Sep 25, 2014·Frontiers in Plant Science·Miguel Moreno-GarcíaHumberto Lanz-Mendoza
Oct 21, 2005·Trends in Parasitology·Luke A Baton, Lisa C Ranford-Cartwright
Jul 14, 2010·International Journal for Parasitology·Ann-Kristin MuellerKristin Michel
Jul 13, 2006·Insect Biochemistry and Molecular Biology·Eric CalvoJosé M C Ribeiro
Jul 24, 2010·Law & Society Review·Jean-Louis Van Gelder
Jan 25, 2020·International Journal of Molecular Sciences·Berlin Londono-RenteriaAnd Audrey E Lenhart
May 17, 2018·Scientific Reports·V A BrugmanT Walker
Oct 31, 2020·Biology of the Cell·Melika HajkazemianS Noushin Emami
Jun 24, 2006·Current Opinion in Genetics & Development·Dina VlachouFotis C Kafatos

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.