Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals.

Journal of Veterinary Pharmacology and Therapeutics
D T VoR J Martin

Abstract

Fleas are significant ectoparasites of small animals. They can be a severe irritant to animals and serve as a vector for a number of infectious diseases. In this article, we discuss the pharmacological characteristics of four insect nicotinic acetylcholine receptor (nAChR) agonists used as flea adulticides in dogs and cats, which include three neonicotinoids (imidacloprid, nitenpyram, and dinotefuran) and a macrocyclic lactone (spinosad). Insect nAChR agonists are one of the most important classes of insecticides, which are used to control sucking insects on both plants and animals. These novel compounds provide a new approach for practitioners to safely and effectively eliminate adult fleas.

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Citations

Mar 3, 2012·The Veterinary Clinics of North America. Small Animal Practice·Tina Wismer, Charlotte Means
Nov 19, 2010·Journal of Veterinary Pharmacology and Therapeutics·T L HallN Pusterla
Oct 19, 2010·Journal of Veterinary Pharmacology and Therapeutics·H K Dimaio KnychS D Stanley
Apr 16, 2011·Journal of Veterinary Pharmacology and Therapeutics·J N KingP Lees
Oct 19, 2010·Journal of Veterinary Pharmacology and Therapeutics·L WintherC Friis
May 28, 2011·Journal of Veterinary Pharmacology and Therapeutics·Y H HwangH I Yun

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