Insect sting allergy with negative venom skin test responses

The Journal of Allergy and Clinical Immunology
D B GoldenL M Lichtenstein

Abstract

In our 1976 controlled venom immuno rapy trial, 33% of 182 patients with a history of systemic reactions to insect stings were excluded because of negative venom skin test responses. There have been reports of patients with negative skin test responses who have had severe reactions to subsequent stings. Our aim is to increase awareness about the patient with a negative skin test response and insect sting allergy and to determine the frequency and significance of negative skin test responses in patients with a history of systemic reactions to insect stings. We prospectively examined the prevalence of negative venom skin test responses in patients with a history of systemic reactions to stings. In patients who gave informed consent, we analyzed the outcome of retesting and sting challenge. Of 307 patients with positive histories screened for our sting challenge study, 208 (68%) had positive venom skin test responses (up to 1 microg/mL concentration), and 99 (32%) had negative venom skin test responses. In 36 (36%) of the 99 patients with negative skin test responses, the venom RAST result was a low positive (1-3 ng/mL), or repeat venom skin test responses were positive; another 7 (7%) patients had high venom-specific IgE antibody...Continue Reading

Citations

Oct 26, 2012·International Archives of Allergy and Immunology·S Tolga YavuzAyfer Tuncer
Feb 17, 2011·Immunotherapy·Beatrice M Bilò, Floriano Bonifazi
May 11, 2011·Immunotherapy·David González-de-OlanoLuis Escribano
Apr 11, 2014·The New England Journal of Medicine·Thomas B Casale, A Wesley Burks
May 1, 2005·Expert Review of Clinical Immunology·Didier G EboWim J Stevens
Oct 1, 2008·Expert Opinion on Medical Diagnostics·Robert G Hamilton
Oct 4, 2005·Allergy·B M BilóUNKNOWN EAACI Interest Group on Insect Venom Hypersensitivity
May 18, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S G A BrownR J Heddle
Jul 9, 2004·Current Opinion in Allergy and Clinical Immunology·Robert G Hamilton
Dec 23, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·David B K GoldenDana Wallace
Mar 28, 2017·Allergo Journal International·N WojtalewiczI Schellenberg
Sep 12, 2015·American Journal of Rhinology & Allergy·John Oppenheimer
May 3, 2013·Allergy, Asthma & Immunology Research·Robert D Pesek, Richard F Lockey
Mar 16, 2002·Current Allergy and Asthma Reports·Gerald W Volcheck
Apr 29, 2009·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Yael GraifTamy Shohat
Jun 10, 2010·Cytometry. Part B, Clinical Cytometry·Eva M SturmGunter J Sturm
Oct 23, 2010·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·F RuëffB Przybilla
Jan 22, 2008·International Archives of Allergy and Immunology·K SchererA J Bircher
Jun 19, 2009·Current Opinion in Allergy and Clinical Immunology·Kathrin SchererIngmar Afm Heijnen
Aug 20, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P KorosecM Kosnik
Sep 14, 2011·The Mount Sinai Journal of Medicine, New York·James M Tracy
Jun 26, 2015·Current Opinion in Allergy and Clinical Immunology·James M TracyJohn Carlson
Jul 11, 2007·Current Opinion in Allergy and Clinical Immunology·Arnon Goldberg
Jun 11, 2011·Current Opinion in Allergy and Clinical Immunology·James M TracyJeffrey G Demain
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Leonardo AntonicelliFloriano Bonifazi
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Kalliopi Kontou-Fili
Jun 11, 2014·Current Opinion in Allergy and Clinical Immunology·David B K Golden
Apr 17, 2013·Journal of Paediatrics and Child Health·John W Tan, Dianne E Campbell
Oct 30, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T GülenG Nilsson
Jun 12, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·P M MatricardiM Ollert
Jul 17, 2003·Current Opinion in Allergy and Clinical Immunology·Anthony E J Dubois
Jul 11, 2006·Current Opinion in Allergy and Clinical Immunology·David B K Golden
Aug 30, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L DiwakarM T Krishna
Mar 20, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·P A EigenmannUNKNOWN European Academy of Allergy and Clinical Immunology-Clemens von Pirquet Foundation
Oct 22, 2019·Clinical and Translational Allergy·Danielle FehrPeter Schmid-Grendelmeier
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Robert G Hamilton
Dec 1, 2013·Journal of Pharmacopuncture·Chaeweon Kim, Kwangho Lee
Nov 25, 2003·Southern Medical Journal·John E Moffitt
Jul 11, 2006·Current Opinion in Allergy and Clinical Immunology·Franziska RuëffBernhard Przybilla
Jun 26, 2012·Current Opinion in Allergy and Clinical Immunology·James M TracyJeffrey G Demain
Aug 19, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M T KrishnaUNKNOWN British Society for Allergy and Clinical Immunology
Aug 19, 2005·Postgraduate Medicine·David F Graft

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