Insecticide-treated durable wall lining (ITWL): future prospects for control of malaria and other vector-borne diseases

Malaria Journal
Louisa A Messenger, Mark Rowland

Abstract

While long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of malaria vector control throughout sub-Saharan Africa, there is an urgent need for the development of novel insecticide delivery mechanisms to sustain and consolidate gains in disease reduction and to transition towards malaria elimination and eradication. Insecticide-treated durable wall lining (ITWL) may represent a new paradigm for malaria control as a potential complementary or alternate longer-lasting intervention to IRS. ITWL can be attached to inner house walls, remain efficacious over multiple years and overcome some of the operational constraints of first-line control strategies, specifically nightly behavioural compliance required of LLINs and re-current costs and user fatigue associated with IRS campaigns. Initial experimental hut trials of insecticide-treated plastic sheeting reported promising results, achieving high levels of vector mortality, deterrence and blood-feeding inhibition, particularly when combined with LLINs. Two generations of commercial ITWL have been manufactured to date containing either pyrethroid or non-pyrethroid formulations. While some Phase III trials of these products have demonstrated red...Continue Reading

References

Oct 1, 1995·Medical and Veterinary Entomology·S HewittE Kemp
Jan 4, 2003·Medical and Veterinary Entomology·K GrahamM Rowland
Aug 12, 2004·Tropical Medicine & International Health : TM & IH·Musawenkosi L H MabasoChristian Lengeler
Apr 28, 2006·Tropical Medicine & International Health : TM & IH·A DiabateJ-M Hougard
Aug 16, 2006·Malaria Journal·Claudia FreyOlaf Müller
May 18, 2007·Transactions of the Royal Society of Tropical Medicine and Hygiene·Kate KolaczinskiSylvia Meek
Nov 5, 2011·Malaria Journal·Michael T WhiteAzra C Ghani
May 25, 2013·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Kathleen M MaloneyMichael Z Levy
Jan 31, 2015·PloS One·Humphrey WanzirahSteve W Lindsay

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Citations

Apr 29, 2020·Scientific Reports·Edgar J M PollardThomas R Burkot
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Federica AielloPaulo Dani
Aug 13, 2021·PLoS Neglected Tropical Diseases·Sofia BalaskaJohn Vontas

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