Insemination with border disease virus-infected semen results in seroconversion in cows but not persistent infection in fetuses

BMC Veterinary Research
U BraunMatthias Schweizer

Abstract

This study examined various health variables in cows after artificial insemination with Border disease virus (BDV)-infected semen and the occurrence of persistent infection in ensuing fetuses. Five cows were inseminated (day 0) with BDV-infected semen as well as with semen from a fertile Eringer bull. One cow, inseminated with virus-free semen only, served as a control. Clinical examination, assessment of eating and rumination activities, measurement of intraruminal temperature and leukocyte count were used to monitor the health of the cows. Blood samples were collected at regular intervals for the detection of viral RNA and antibodies against BDV, and the cows were slaughtered on day 56. The uteri, placentae and fetuses were examined macroscopically, histologically, immunohistochemically and by means of molecular methods for the presence of pestiviruses. The demeanour, eating and rumination activities and intraruminal temperature were not affected by insemination with BDV-infected semen, whereas the total leukocyte and lymphocyte counts dropped transiently and were significantly lower on day 6 than on day 0. Seroconversion occurred by day 28 in the five infected cows but not in the control cow. The uteri, placentae and fetuses...Continue Reading

References

Mar 1, 1990·Revue Scientifique Et Technique·J Brownlie
Jun 1, 1997·The Journal of General Virology·P BecherH J Thiel
Aug 19, 2007·The Veterinary Record·M P CranwellT Sandvik
Nov 21, 2008·Veterinary Microbiology·Andrea HornbergKarl Schöpf
May 4, 2012·New Zealand Veterinary Journal·A M J McFaddenA M Weir
Aug 15, 2013·BMC Veterinary Research·Ueli BraunMichael Hässig
Nov 11, 2014·Annual Review of Animal Biosciences·Matthias Schweizer, Ernst Peterhans
Jun 9, 2015·Animal Health Research Reviews·Christopher C L ChaseMrigendra K Rajput
Feb 9, 2017·Schweizer Archiv für Tierheilkunde·U BraunK Nuss

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BETA
biopsy
ELISA
genotyping

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SPSS Statistics

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