Insight into the incidence of acute aortic dissection in the German region of Berlin and Brandenburg

International Journal of Cardiology
S D KurzC Buschmann

Abstract

Stanford acute type A aortic dissection (ATAAD) is a potentially lethal condition. Epidemiology studies show a statistical incidence in Europe of approximately 2-16 cases/100,000 inhabitants/year. In Germany, the estimated incidence (here subsumed under "thoracic aortic dissection" with 4.63 cases/100,000 inhabitants/year) is mainly extracted from medical death certificates by the German Federal Statistical Office. The prehospital incidence of ATAAD deaths is largely unknown. Since patients often die in the pre-hospital setting, the incidence of ATAAD is therefore likely to be higher than current estimates. For the period from 2010 to 2014, we retrospectively analyzed all in-hospital ATAAD data from two of the largest cardiac surgical centers that treat ATAAD in the Berlin-Brandenburg region. In addition, autopsy reports of all forensic medicine institutes and of one large pathological provider in the region were analyzed to identify additional non-hospitalized ATAAD patients. Based on these findings, the regional incidence of ATAAD was calculated. In addition to in-hospital ATAAD patients (n=405), we identified additional 145 lethal ATAAD cases among 14,201 autopsy reports. The total of 550 ATAAD cases led to an estimated inci...Continue Reading

Citations

Feb 24, 2018·Interactive Cardiovascular and Thoracic Surgery·Uyanga AdamStephan Dominik Kurz
Dec 14, 2018·Forensic Science, Medicine, and Pathology·Claas T Buschmann
May 6, 2020·Scientific Reports·Maximilian WundramStephan D Kurz
Feb 12, 2021·Scientific Reports·Caleb R MatthewsLawrence S Lee
Apr 7, 2021·Surgical Technology International·Leonard PittsJörg Kempfert

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