INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma

Future Oncology
Caitlin CostelloVania Hungria

Abstract

With the introduction of new drugs with different mechanisms of action, multiple myeloma (MM) patients' outcomes have improved. However, the efficacy seen in clinical trials is often not seen in real-world settings and data on the effectiveness of MM therapies are needed. INSIGHT MM is a prospective, global, non-interventional, observational study that is enrolling approximately 4200 patients with newly diagnosed or relapsed/refractory MM, making it the largest study of its kind to date. The study aims to describe contemporary, real-world patterns of patient characteristics, clinical disease presentation, therapies chosen, clinical outcomes (response, treatment duration, time-to-next-therapy, progression-free and overall survival), safety, healthcare resource utilization and quality of life. One interim analysis has been conducted to date; current accrual is approximately 3094 patients. Trial registration number: NCT02761187.

References

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Citations

Jul 7, 2020·Leukemia & Lymphoma·Shebli AtrashSaad Z Usmani
Oct 31, 2020·Cancers·Daniela IannazzoAlessandra Bitto
Mar 15, 2021·Clinical Lymphoma, Myeloma & Leukemia·Ioannis Ntanasis-StathopoulosMeletios A Dimopoulos
Nov 5, 2021·JCO Clinical Cancer Informatics·Sundar JagannathNoopur Raje

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Methods Mentioned

BETA
ISS
Fluorescence

Clinical Trials Mentioned

NCT01818752
NCT01554852
NCT02412878
NCT03608501
NCT02410694
NCT02252172
NCT02874742
NCT02541383
NCT03158688
NCT01335399

Software Mentioned

INSIGHT MM
INSIGHT

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