Insights from the dabigatran versus warfarin in patients with atrial fibrillation (RE-LY) trial

Expert Opinion on Pharmacotherapy
Chee W Khoo, Gregory Y H Lip

Abstract

Oral anticoagulants such as warfarin have been used widely for the treatment of venous thromboembolism and stroke prevention in atrial fibrillation (AF) patients. Warfarin has significant limitations and also requires frequent monitoring. Thus, there is an unmet need, with the quest for alternative oral anticoagulants with stable pharmacokinetics and pharmacodynamics that do not need monitoring. The paper under evaluation provides us with up-to-date information on the safety and efficacy of a new oral anticoagulant, dabigatran, compared with warfarin for stroke prevention in AF patients.

References

May 30, 2006·European Heart Journal·Robby NieuwlaatUNKNOWN Euro Heart Survey Investigators
Sep 22, 2006·Journal of Clinical Pharmacology·Stephen P Glasser, George Howard
Sep 1, 2009·The New England Journal of Medicine·Stuart J ConnollyUNKNOWN RE-LY Steering Committee and Investigators

❮ Previous
Next ❯

Citations

Jan 25, 2011·Expert Opinion on Pharmacotherapy·Mariano A GiorgiGuillermo Di Girolamo
Jul 21, 2020·Journal of Health Economics and Outcomes Research·Roland Diel, Niklas Lampenius
Jul 18, 2017·Case Reports in Cardiology·Munish SharmaKoroush Khalighi
Nov 28, 2019·Journal of Interventional Cardiology·Pierluigi MerellaGavino Casu
Nov 9, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Seungwon KwonMin-Jeong Park

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.