Insights into eisosome assembly and organization.

Journal of Biosciences
Murphy E R, Kim K T

Abstract

Eisosomes, large protein complexes that are predominantly composed of BAR-domain-containing proteins Pil1 and its homologs, are situated under the plasma membrane of ascomycetes. A successful targeting of Pil1 onto the future site of eisosome accompanies maturation of eisosome. During or after recruitment, Pil1 undergoes self-assembly into filaments that can serve as scaffolds to induce membrane furrows or invaginations. Although a consequence of the invagination is likely to redistribute particular proteins and lipids to a different location, the precise physiological role of membrane invagination and eisosome assembly awaits further investigation. The present review summarizes recent research findings within the field regarding the detailed structural and functional significance of Pil1 on eisosome organization.

References

Mar 13, 1999·Current Biology : CB·A CasamayorD R Alessi
Mar 15, 2000·Proceedings of the National Academy of Sciences of the United States of America·M BagnatK Simons
Apr 20, 2000·The Journal of Biological Chemistry·D A Brown, E London
Jun 28, 2002·The Journal of Biological Chemistry·Gongshe HanTeresa M Dunn
Nov 26, 2002·The Journal of Biological Chemistry·John D HearnRobert C Dickson
Oct 11, 2003·Molecular Biology of the Cell·Katerina MalínskáWidmar Tanner
Jan 15, 2005·Biochemical Society Symposium·Jennifer L Gallop, Harvey T McMahon
Feb 24, 2006·Nature·Tobias C WaltherPeter Walter
Mar 27, 2007·Biochimica Et Biophysica Acta·Thomas Strahl, Jeremy Thorner
Nov 24, 2007·The EMBO Journal·Tobias C WaltherPeter Walter
Feb 26, 2008·The Journal of Biological Chemistry·Guangzuo LuoRobert C Dickson
Dec 10, 2008·The Journal of Cell Biology·Guido GrossmannWidmar Tanner
Jan 16, 2009·Molecular Biology of the Cell·Doris Berchtold, Tobias C Walther
Mar 10, 2009·Molecular & Cellular Proteomics : MCP·Changhui DengAndrew N Krutchinsky
Apr 22, 2009·Cell·Adam FrostPietro De Camilli
Jul 1, 2009·The Journal of Cell Biology·Florian FröhlichTobias C Walther
Jul 30, 2009·Journal of Cell Science·Vendula StrádalováJan Malinsky
Dec 8, 2009·Seminars in Cell & Developmental Biology·Shiro SuetsuguYosuke Senju
Jan 2, 2010·Science·Daniel Lingwood, Kai Simons
Aug 10, 2010·Eukaryotic Cell·Ioannis VangelatosVicky Sophianopoulou
Jan 13, 2011·Journal of Cell Science·Thorsten BrachMarko Kaksonen
Apr 20, 2011·Expert Review of Proteomics·Simon Staubach, Franz-Georg Hanisch
Apr 29, 2011·Journal of Cell Science·Shanon SegerPeter Philippsen
May 20, 2011·Molecular Biology of the Cell·Agustina Olivera-CoutoPablo S Aguilar
Jun 21, 2011·Nature Structural & Molecular Biology·Natasza E ZiółkowskaTobias C Walther
Sep 9, 2011·Molecular Biology of the Cell·Ruth KabecheJames B Moseley
Nov 11, 2011·Atherosclerosis·Stéphanie Lemaire-EwingDominique Néel
Nov 30, 2011·The Journal of Cell Biology·Lena KarotkiTobias C Walther

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Citations

Jul 9, 2014·Annual Review of Microbiology·Lois M Douglas, James B Konopka
Oct 19, 2017·DNA and Cell Biology·Chelsea M WintersHui-Ling Chiang
Feb 28, 2016·The Journal of Microbiology·Lois M Douglas, James B Konopka
Jan 27, 2018·Journal of Fungi·Jenna E FoderaroJames B Konopka
Feb 26, 2019·Frontiers in Pharmacology·Tomas Di MambroEmanuele Marra

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