Insights into the evolution of mitochondrial genome size from complete sequences of Citrullus lanatus and Cucurbita pepo (Cucurbitaceae).

Molecular Biology and Evolution
Andrew J AlversonJeffrey D Palmer

Abstract

The mitochondrial genomes of seed plants are unusually large and vary in size by at least an order of magnitude. Much of this variation occurs within a single family, the Cucurbitaceae, whose genomes range from an estimated 390 to 2,900 kb in size. We sequenced the mitochondrial genomes of Citrullus lanatus (watermelon: 379,236 nt) and Cucurbita pepo (zucchini: 982,833 nt)--the two smallest characterized cucurbit mitochondrial genomes--and determined their RNA editing content. The relatively compact Citrullus mitochondrial genome actually contains more and longer genes and introns, longer segmental duplications, and more discernibly nuclear-derived DNA. The large size of the Cucurbita mitochondrial genome reflects the accumulation of unprecedented amounts of both chloroplast sequences (>113 kb) and short repeated sequences (>370 kb). A low mutation rate has been hypothesized to underlie increases in both genome size and RNA editing frequency in plant mitochondria. However, despite its much larger genome, Cucurbita has a significantly higher synonymous substitution rate (and presumably mutation rate) than Citrullus but comparable levels of RNA editing. The evolution of mutation rate, genome size, and RNA editing are apparently d...Continue Reading

References

Apr 1, 1992·Trends in Genetics : TIG·C AndréV Walbot
Apr 1, 1990·Trends in Genetics : TIG·J D Palmer
May 1, 1990·Current Genetics·D J CummingsE T Matsuura
Dec 22, 1989·Science·R HieselA Brennicke
Oct 1, 1989·Plant Molecular Biology·C L Hsu, B C Mullin
Dec 1, 1988·Journal of Molecular Evolution·J D Palmer, L A Herbon
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·K H WolfeP M Sharp
Jul 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·R Kolodner, K K Tewari
Jun 12, 1996·Molecular & General Genetics : MGG·G PerrottaC Quagliariello
May 16, 1998·Genome Research·D GordonP Green
May 14, 1999·Molecular & General Genetics : MGG·M HoffmannS Binder
Oct 6, 1999·Genome Research·X Huang, A Madan
Dec 28, 1999·Proceedings of the National Academy of Sciences of the United States of America·P Giegé, A Brennicke
Jul 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Keith L AdamsJeffrey D Palmer
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Apr 17, 2004·Science·Joseph P Polski
Apr 17, 2004·Science·Alexander E Vinogradov
Jun 8, 2004·Bioinformatics·Stacia K WymanJeffrey L Boore
Jul 14, 2004·Current Genetics·Beth A RowanArnold J Bendich
Nov 16, 2004·Plant Physiology·Sandra W CliftonKathleen J Newton
Dec 9, 2004·Nucleic Acids Research·David ChouryAlejandro Araya
Dec 16, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ulfar BergthorssonJeffrey D Palmer
Nov 11, 2005·Molecular Biology and Evolution·Michael Lynch
Mar 25, 2006·Science·Michael LynchSarah Schaack
Jun 1, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Mizuho SatohTetsuo Mikami
Jul 25, 2006·Molecular Genetics and Genomics : MGG·Jeffrey P Mower, Jeffrey D Palmer

❮ Previous
Next ❯

Citations

Feb 13, 2013·Journal of Molecular Evolution·Juan P Jaramillo-CorreaJean Bousquet
Oct 21, 2011·Omics : a Journal of Integrative Biology·Himani Kuntal, Vinay Sharma
Jun 25, 2013·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Reetu TutejaRajeev K Varshney
Oct 12, 2010·Nucleic Acids Research·Cestmir VlcekGertraud Burger
Nov 17, 2010·BMC Plant Biology·Chris CarrieJames Whelan
Jun 23, 2011·PLoS Genetics·Michael Lynch
Oct 12, 2012·PloS One·Wenqin WangJoachim Messing
Jan 25, 2014·Molecular Biology and Evolution·Jeanmaire MolinaMichael D Purugganan
Jan 28, 2014·BMC Genomics·Andrzej K NoyszewskiShahryar F Kianian
Feb 12, 2014·Proceedings of the National Academy of Sciences of the United States of America·Logan KistlerBeth Shapiro
Jul 2, 2014·Molecular Biology and Evolution·Yang LiuBernard Goffinet
Dec 30, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Ye XiongZongyun Li
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Da-Shi QiYe Xiong
May 7, 2015·Proceedings of the National Academy of Sciences of the United States of America·Zhiqiang WuDaniel B Sloan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.