Insights into the life cycle of yeasts from the CTG clade revealed by the analysis of the Millerozyma (Pichia) farinosa species complex.

PloS One
Sandrine MalletSerge Casaregola

Abstract

Among ascomycetous yeasts, the CTG clade is so-called because its constituent species translate CTG as serine instead of leucine. Though the biology of certain pathogenic species such as Candida albicans has been much studied, little is known about the life cycles of non-pathogen species of the CTG clade. Taking advantage of the recently obtained sequence of the biotechnological Millerozyma (Pichiasorbitophila) farinosa strain CBS 7064, we used MLST to better define phylogenic relationships between most of the Millerozyma farinosa strains available in public collections. This led to the constitution of four phylogenetic clades diverging from 8% to 15% at the DNA level and possibly constituting a species complex (M. farinosa) and to the proposal of two new species:Millerozyma miso sp. nov. CBS 2004(T) ( = CLIB 1230(T)) and Candida pseudofarinosa sp. nov.NCYC 386(T)( = CLIB 1231(T)). Further analysis showed that M. farinosa isolates exist as haploid and inter-clade hybrids. Despite the sequence divergence between the clades, secondary contacts after reproductive isolation were evidenced, as revealed by both introgression and mitochondria transfer between clades. We also showed that the inter-clade hybrids do sporulate to generate...Continue Reading

References

Jan 1, 1977·Antonie van Leeuwenhoek·J P van der WaltN V Liebenberg
Feb 28, 1975·Mycopathologia·C P KurtzmanF L Baker
May 1, 1989·Reviews of Infectious Diseases·E AnaissieK Rolston
Jan 1, 1980·Antonie van Leeuwenhoek·L Rodriques de MirandaH Seyfarth
Jan 1, 1996·Mycopathologia·P García-MartosJ M Hernández
Oct 6, 1998·Applied and Environmental Microbiology·I MasneufD Dubourdieu
Oct 8, 1999·Antonie van Leeuwenhoek·H PrillingerK Lopandic
Nov 11, 1999·International Journal of Systematic Bacteriology·C GrothJ Piskur
Dec 21, 2000·Trends in Microbiology·K H Berger, M P Yaffe
Aug 9, 2001·International Journal of Systematic and Evolutionary Microbiology·H M DanielW Meyer
Jan 7, 2003·Applied and Environmental Microbiology·Fernando RodriguesCecília Leão
Jun 5, 2003·Antonie van Leeuwenhoek·Mauricio CorredorClaude Gaillardin
Oct 8, 2003·Systematic Biology·Stéphane Guindon, Olivier Gascuel
Mar 17, 2004·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Ruth E FundygaTimothy J Lott
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Jul 2, 2004·Nature·Bernard DujonJean-Luc Souciet
Jan 7, 2005·Journal of Clinical Microbiology·Arianna TavantiFrank C Odds
Jan 22, 2005·Nucleic Acids Research·Kazutaka KatohTakashi Miyata
Apr 27, 2005·FEMS Yeast Research·Stephen A JamesIan N Roberts
May 25, 2005·Annual Review of Microbiology·R J Bennett, A D Johnson
Feb 20, 2007·Current Biology : CB·Heidi A KuehnePaul D Sniegowski
Aug 19, 2007·Journal of Clinical Microbiology·A AdlerI Polacheck
Feb 26, 2008·Applied and Environmental Microbiology·Sara S GonzálezAmparo Querol
Mar 6, 2008·FEMS Yeast Research·Sandra RainieriPaolo Giudici
Aug 5, 2008·FEMS Yeast Research·Christine SacerdotOdile Ozier-Kalogeropoulos
Apr 21, 2009·Methods in Molecular Biology·Kazutaka KatohHiroyuki Toh
May 2, 2009·International Journal of Systematic and Evolutionary Microbiology·Noémie JacquesSerge Casaregola
May 26, 2009·Nature·Geraldine ButlerChristina A Cuomo
Jul 15, 2009·FEMS Yeast Research·Paul P JungJacky de Montigny
Sep 12, 2009·Genome Research·Andrew P JacksonMatthew Berriman

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Citations

Dec 7, 2014·Antonie van Leeuwenhoek·Noémie JacquesSerge Casaregola
Jul 1, 2016·Applied Microbiology and Biotechnology·Christoph BuerthJoachim F Ernst
Apr 9, 2017·World Journal of Microbiology & Biotechnology·Rosa SantomartinoMichele M Bianchi
Jun 29, 2017·Annual Review of Microbiology·Kenneth H Wolfe, Geraldine Butler

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Methods Mentioned

BETA
electrophoresis
PCR
flow-cytometry
flow cytometry
two
Fluorescence

Software Mentioned

Muscle
MAFFT
BLAST
Phyml
ClustalX

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