Insomnia in patients with depression: a STAR*D report

CNS Spectrums
Prabha SunderajanMadhukar H Trivedi

Abstract

Insomnia symptoms, which are common in depression, have a significant impact on function and quality of life. However, little is known about the prevalence and associated features of insomnia symptoms in representative treatment-seeking patients with depression. Data from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial were analyzed. STAR*D recruited 3,743 adult outpatients diagnosed with nonpsychotic major depressive disorder (MDD) from primary (n=18) and psychiatric care (n=23) clinics across the United States. Baseline sociodemographic and clinical features were compared between those with insomnia symptoms (84.7%) and those without (15.3%). The most common presentation was the simultaneous presence of sleep onset, mid-nocturnal, and early morning insomnia symptoms (27.1%). Of these three types of insomnia symptoms, mid-nocturnal insomnia symptoms were the most commonly found alone (13.5%) and in combination with one or more other types (82.3%). Insomnia symptoms were associated with several indicators of a more severe depressive illness. Only a small proportion of participants with insomnia symptoms were receiving treatment for sleep disturbances at study initiation, and the vast majority of those ...Continue Reading

References

Sep 1, 1974·Archives of General Psychiatry·P HauriJ Mendels
May 1, 1968·Journal of the American Geriatrics Society·B S LinnL Gurel
Feb 1, 1997·Journal of Affective Disorders·M L PerlisD J Kupfer
Jun 1, 1997·The Journal of Clinical Psychiatry·M Y AğargünM Solmaz
Jul 15, 1997·American Journal of Epidemiology·P P ChangM J Klag
Oct 27, 1997·The American Journal of Psychiatry·G E Simon, M VonKorff
Nov 11, 1998·Nature Medicine·A D Lopez, C C Murray
Apr 30, 1999·The Journal of Clinical Psychiatry·A A NierenbergM Fava
May 12, 2001·Comprehensive Psychiatry·M Zimmerman, J I Mattia
Sep 25, 2001·Depression and Anxiety·D E Ford, L Cooper-Patrick
May 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·James C MundtJohn H Greist
Dec 17, 2002·Journal of Psychiatric Research·Maurice M Ohayon, Thomas Roth
Jan 18, 2003·Sleep Medicine Reviews·Maurice M Ohayon
Jan 18, 2003·Sleep Medicine Reviews·Lisa Lustberg, Charles F. Reynolds
Jun 5, 2003·The Psychiatric Clinics of North America·Maurizio FavaDavid J Kupfer
Aug 2, 2003·Biological Psychiatry·Bruce Rudisch, Charles B Nemeroff
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Mar 17, 2004·Journal of Affective Disorders·Pim CuijpersSaskia van Dorsselaer
Apr 6, 2004·Controlled Clinical Trials·A John RushUNKNOWN STAR*D Investigators Group
Apr 6, 2004·Sleep Medicine Reviews·Ripu D Jindal, Michael E Thase
Jun 16, 2004·Archives of Internal Medicine·Patricia K Corey-LisleRalph Swindle
Jul 21, 2004·Psychiatry Research·Ariane Marie-MitchellStanley P Azen
Aug 5, 2004·CNS Drugs·François-André Allaert, Renaud Urbinelli
May 25, 2005·Journal of Epidemiology and Community Health·Ying-Yeh ChenYue-Joe Lee
Jul 5, 2005·Journal of Psychiatric Research·Rachel ManberMartin B Keller
Mar 15, 2006·The Journal of Nervous and Mental Disease·Mark ZimmermanIwona Chelminski
Aug 30, 2006·Journal of Affective Disorders·Mehmet Yucel AgargunYavuz Selvi
Jul 31, 2007·Psychiatry Research·Sarah Laxhmi Chellappa, John Fontenele Araújo
Aug 19, 2007·Psychotherapy and Psychosomatics·Giovanni A FavaSilvana Grandi
Jul 21, 2009·Journal of Psychosomatic Research·Børge SivertsenArnstein Mykletun

❮ Previous
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Citations

Sep 25, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi HurTim D Spector
Jan 30, 2014·Psychiatry Investigation·Seon-Cheol ParkYong Chon Park
Dec 7, 2013·Journal of Neural Transmission·J Thome, P Foley
Mar 25, 2019·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·I-Mei LinYu-Che Tsai
Jan 20, 2012·Journal of Child and Adolescent Psychopharmacology·Graham J EmsliePaul Croarkin
Aug 7, 2012·Current Psychiatry Reports·Chiara Baglioni, Dieter Riemann
May 20, 2015·European Child & Adolescent Psychiatry·Stephanie GestTanja Legenbauer
Dec 10, 2016·Journal of Mental Health·Lee Seng Esmond SeowSiow Ann Chong
Aug 17, 2019·Sleep·Emerson M WickwireJennifer S Albrecht
Oct 31, 2012·BMC Psychiatry·Håvard KallestadRolf W Gråwe
Dec 23, 2016·Current Sleep Medicine Reports·Markus Jansson-Fröjmark, Annika Norell-Clarke
Sep 8, 2018·The Australian and New Zealand Journal of Psychiatry·Nick GlozierLee Ritterband
Feb 20, 2020·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Maryam ShayestehFatemeh Heidary
Oct 31, 2015·International Journal of Psychiatry in Medicine·Suma P Chand
Sep 3, 2010·Journal of Behavioral Medicine·Kelly Glazer BaronDavid C Mohr
Jun 24, 2017·Journal of Behavioral Medicine·Diana A ChirinosAllan I Pack
May 20, 2018·Scientific Reports·Uri KartounStanley Y Shaw
Mar 6, 2021·Sleep Medicine Reviews·Gavin BrupbacherArno Schmidt-Trucksäss
Nov 19, 2018·General Hospital Psychiatry·Faith O NomamiukorAnka A Vujanovic
Jun 4, 2021·Nature and Science of Sleep·Jooyoung LeeSeog Ju Kim

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