Instant Clue: A Software Suite for Interactive Data Visualization and Analysis

Scientific Reports
Hendrik NolteMarcus Krüger

Abstract

The development of modern high-throughput instrumentation and improved core facility infrastructures leads to an accumulation of large amounts of scientific data. However, for a majority of scientists the comprehensive analysis and visualization of their data goes beyond their expertise. To reduce this hurdle, we developed a software suite called Instant Clue that helps scientists to visually analyze data and to gain insights into biological processes from their high-dimensional dataset. Instant Clue combines the power of visual and statistical analytics using a straight forward drag & drop approach making the software highly intuitive. Additionally, it offers a comprehensive portfolio of statistical tools for systematic analysis such as dimensional reduction, (un)-supervised learning, clustering, multi-block (omics) integration and curve fitting. Charts can be combined with high flexibility into a main figure template for direct usage in scientific publications. Even though Instant Clue was developed with the omics-sciences in mind, users can analyze any kind of data from low to high dimensional data sets. The open-source software is available for Windows and Mac OS ( http://www.instantclue.uni-koeln.de ) and is accompanied by...Continue Reading

References

May 6, 2008·Bioinformatics·Ashoka D PolpitiyaRichard D Smith
May 24, 2011·Molecular & Cellular Proteomics : MCP·Kristoffer T G RigboltBlagoy Blagoev
Mar 12, 2013·Computational and Mathematical Methods in Medicine·Chunmei LiuYinglei Song
Nov 22, 2013·Journal of Cell Science·Christoph Sommer, Daniel W Gerlich
Feb 20, 2014·Biostatistics·Arthur TenenhausVincent Frouin
Feb 24, 2015·Cell·Yiming ChenZachary A Knight
Oct 10, 2015·Nucleic Acids Research·Sarah E CalvoVamsi K Mootha
Dec 18, 2015·Nucleic Acids Research·Robert D FinnAlex Bateman
Jun 11, 2016·Science·Evan G WilliamsJohan Auwerx
Jun 28, 2016·Nature Methods·Stefka TyanovaJürgen Cox
Mar 14, 2017·Nature Cell Biology·Shotaro SaitaThomas Langer
May 19, 2017·Nucleic Acids Research·Georgios EfstathiouIoannis Iliopoulos
Jun 12, 2017·Cell Systems·Dorte B Bekker-JensenJesper V Olsen

❮ Previous
Next ❯

Citations

Nov 18, 2018·Electrophoresis·Biswapriya B Misra, Subhashree Mohapatra
Oct 28, 2019·Journal of Cachexia, Sarcopenia and Muscle·Martina BaraldoBert Blaauw
Mar 7, 2020·Molecular & Cellular Proteomics : MCP·Eva GriesserAngus I Lamond
May 12, 2020·Nucleic Acids Research·Federico TavernaPeter Carmeliet
Jun 25, 2020·PLoS Genetics·Emma B AlmeDavid P Toczyski
Jun 26, 2020·Molecular & Cellular Proteomics : MCP·Frederik TellkampMarcus Krüger
Jun 17, 2020·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Jade G M LoggerPiet E J van Erp
Apr 10, 2020·Nature Communications·Lucie LaurienManolis Pasparakis
Jun 13, 2020·International Journal of Molecular Sciences·Veronika S GeorgievaBent Brachvogel
Jul 6, 2020·Nucleic Acids Research·Jennifer V GerbrachtNiels H Gehring
Nov 27, 2019·Sensors·Eric S McLamoreEvangelyn C Alocilja
Feb 23, 2020·Bioinformatics and Biology Insights·Indhupriya SubramanianKrishanpal Anamika
Nov 7, 2019·Nature·Thomas MacVicarThomas Langer
Nov 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hana DufkováMartin Černý
Dec 1, 2020·Frontiers in Plant Science·Miroslav BerkaMartin Černý
Jul 17, 2020·Computational and Structural Biotechnology Journal·George MinadakisGeorge M Spyrou
Sep 3, 2020·Biochimica Et Biophysica Acta. Molecular Basis of Disease·Concetta ScimoneAntonina Sidoti
Oct 22, 2020·Journal of Integrative Plant Biology·M Estrella SantamariaManuel Martinez
Jan 17, 2021·Molecular & Cellular Proteomics : MCP·Eva GriesserAngus I Lamond
Feb 8, 2021·Journal of Molecular and Cellular Cardiology·Sriram AravamudhanMarcus Krüger
Feb 12, 2021·Science Translational Medicine·Mahmoud AbdellatifSimon Sedej
Jan 17, 2021·Molecular & Cellular Proteomics : MCP·Frederik TellkampMarcus Krüger
Feb 23, 2021·Frontiers in Plant Science·Sylva PrerostovaRadomira Vankova
Aug 14, 2020·Journal of Cell Science·Francesco BaschieriGuillaume Montagnac
Apr 28, 2021·Nature Metabolism·Hans-Georg SprengerThomas Langer
May 4, 2021·Biochimica Et Biophysica Acta. Bioenergetics·Hendrik Nolte, Thomas Langer
May 6, 2021·Cellular and Molecular Life Sciences : CMLS·Stefan DüsterhöftAndreas Ludwig
Jun 23, 2021·Nature Communications·Nils C GassenMarcel A Müller
Jun 23, 2021·Scientific Reports·Alejandro GarciaManuel Martinez
Jun 24, 2021·Acta Neuropathologica Communications·Ching-Pang ChangYijuang Chern

❮ Previous
Next ❯

Methods Mentioned

BETA
immunoprecipitation
PCA

Software Mentioned

Orange
seaborn
KNIME
Polaris
Active Tcl
scikit
Voyager
learn
Vega
Tableau

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.